[HTML][HTML] Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

M Dusinska, J Tulinska, N El Yamani… - Food and Chemical …, 2017 - Elsevier
The unique properties of nanomaterials (NMs) are beneficial in numerous industrial and
medical applications. However, they could also induce unintended effects. Thus, a proper …

Genotoxicity of nanomaterials: Advanced in vitro models and high throughput methods for human hazard assessment—A review

Y Kohl, E Rundén-Pran, E Mariussen, M Hesler… - Nanomaterials, 2020 - mdpi.com
Changes in the genetic material can lead to serious human health defects, as mutations in
somatic cells may cause cancer and can contribute to other chronic diseases. Genotoxic …

A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective

KM Siivola, MJ Burgum, B Suárez-Merino… - Particle and fibre …, 2022 - Springer
The number of publications in the field of nanogenotoxicology and the amount of
genotoxicity data on nanomaterials (NMs) in several databases generated by European …

[HTML][HTML] Assessing the Toxicity of Metal-and Carbon-Based Nanomaterials In Vitro: Impact on Respiratory, Intestinal, Skin, and Immune Cell Lines

J Carrillo-Romero, G Mentxaka… - International Journal of …, 2024 - mdpi.com
The field of nanotechnology has experienced exponential growth, with the unique properties
of nanomaterials (NMs) being employed to enhance a wide range of products across …

Particle safety assessment in additive manufacturing: From exposure risks to advanced toxicology testing

A Alijagic, M Engwall, E Särndahl, H Karlsson… - Frontiers in …, 2022 - frontiersin.org
Additive manufacturing (AM) or industrial three-dimensional (3D) printing drives a new
spectrum of design and production possibilities; pushing the boundaries both in the …

Different sensitivity of advanced bronchial and alveolar mono-and coculture models for hazard assessment of nanomaterials

E Elje, E Mariussen, E McFadden, M Dusinska… - Nanomaterials, 2023 - mdpi.com
For the next-generation risk assessment (NGRA) of chemicals and nanomaterials, new
approach methodologies (NAMs) are needed for hazard assessment in compliance with the …

NanoGenotoxicology: present and the future

SH Doak, M Dusinska - Mutagenesis, 2017 - academic.oup.com
This Mutagenesis special issue is on the topic of nanogenotoxicology. It unites a collection
of reports that provide insight into:(i) the properties of engineered nanomaterials (ENMs) that …

In vitro approaches for assessing the genotoxicity of nanomaterials

M Dusinska, E Mariussen, E Rundén-Pran… - … : methods and protocols, 2019 - Springer
Genotoxicity is associated with serious health effects and includes different types of DNA
lesions, gene mutations, structural chromosome aberrations involving breakage and/or …

Advanced respiratory models for hazard assessment of nanomaterials—Performance of Mono-, Co-and Tricultures

LMA Camassa, E Elje, E Mariussen, EM Longhin… - Nanomaterials, 2022 - mdpi.com
Advanced in vitro models are needed to support next-generation risk assessment (NGRA),
moving from hazard assessment based mainly on animal studies to the application of new …

Biological properties of low-toxicity PLGA and PLGA/PHB fibrous nanocomposite implants for osseous tissue regeneration. Part I: Evaluation of potential biotoxicity

I Krucińska, B Żywicka, A Komisarczyk… - Molecules, 2017 - mdpi.com
In response to the demand for new implant materials characterized by high biocompatibility
and bioresorption, two prototypes of fibrous nanocomposite implants for osseous tissue …