Exploring the role of a novel postbiotic bile acid: Interplay with gut microbiota, modulation of the farnesoid X receptor, and prospects for clinical translation

B Wang, D Han, X Hu, J Chen, Y Liu, J Wu - Microbiological Research, 2024 - Elsevier
The gut microbiota, mainly resides in the colon, possesses a remarkable ability to
metabolize different substrates to create bioactive substances, including short-chain fatty …

Assessing live microbial therapeutic transmission

JJ Faith - Gut Microbes, 2025 - Taylor & Francis
The development of fecal microbiota transplantation and defined live biotherapeutic
products for the treatment of human disease has been an empirically driven process yielding …

Gut microbiota strain richness is species specific and affects engraftment

A Chen-Liaw, V Aggarwala, I Mogno, C Haifer, Z Li… - Nature, 2024 - nature.com
Despite the fundamental role of bacterial strain variation in gut microbiota function,,,,–, the
number of unique strains of a species that can stably colonize the human intestine is still …

[HTML][HTML] The presence of Clostridioides difficile in faeces before and after faecal microbiota transplantation and its relation with recurrent C. difficile infection and the …

B Groenewegen, E van Lingen, A Kovynev… - Clinical Microbiology …, 2024 - Elsevier
Objectives The objectives of this study are to investigate the presence of Clostridioides
difficile in faeces of patients with recurrent C. difficile infection (rCDI) before and after faecal …

[HTML][HTML] Impact of gut microbiota and its metabolites on immunometabolism in colorectal cancer

M Flory, P Bravo, A Alam - Immunometabolism, 2024 - journals.lww.com
Colorectal cancer (CRC) is highly prevalent, accounting for approximately one-tenth of
cancer cases and deaths globally. It stands as the second most deadly and third most …

Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantation

S Ji, F Ahmad, B Peng, Y Yang, M Su, X Zhao… - 2024 - researchsquare.com
Background Fecal microbiota transplantation (FMT) is widely used to treat severe infections
and investigated for treatment of complex diseases. The therapeutic efficacy of FMT is …

[HTML][HTML] Metagenomic changes in response to antibiotic treatment in severe orthopedic trauma patients

A Kouraki, AS Zheng, S Miller, A Kelly, W Ashraf… - Iscience, 2024 - cell.com
We investigated changes in microbiome composition and abundance of antimicrobial
resistance (AMR) genes post-antibiotic treatment in severe trauma patients. Shotgun …