Biochemistry and use of soybean isoflavones in functional food development

C Hu, WT Wong, R Wu, WF Lai - Critical Reviews in Food Science …, 2020 - Taylor & Francis
Soybeans and their food products exist in the market in various forms, ranging from crude
oils and bean meals to nutritious products (eg soy milk powers). With the availability of …

[HTML][HTML] Targeting miRNAs by natural products: A new way for cancer therapy

B Zhang, L Tian, J Xie, G Chen, F Wang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression through
mRNA degradation or translation inhibition. MiRNAs play important roles in a variety of …

Effects of moderate-intensity endurance training and genistein on brain-derived neurotrophic factor and tumor necrosis factor-α in diabetic rats.

OR Salehi, SA Hosseini, F Farkhaei… - Journal of Nutrition …, 2019 - search.ebscohost.com
Introduction: Diabetes is a metabolic disease that affects the neural and immune system,
causing long-term health complications such as neuropathy and nephropathy. Considering …

Physical exercise and the functions of microRNAs

JAC Dos Santos, ASC Veras, VRG Batista… - Life sciences, 2022 - Elsevier
MicroRNAs (miRNAs) control RNA translation and are a class of small, tissue-specific, non-
protein-coding RNAs that maintain cellular homeostasis through negative gene regulation …

Modulation of microRNAs as a potential molecular mechanism involved in the beneficial actions of physical exercise in Alzheimer disease

AC Improta-Caria, CKV Nonaka… - International journal of …, 2020 - mdpi.com
Alzheimer disease (AD) is one of the most common neurodegenerative diseases, affecting
middle-aged and elderly individuals worldwide. AD pathophysiology involves the …

Mental health benefits of exercise and genistein in elderly rats

SA Hosseini, O Salehi, F Keikhosravi… - Experimental aging …, 2022 - Taylor & Francis
Elderly is a part of life that is associated with physical and mental disorders. The present
study aimed to investigate the effect of 8 weeks of high-intensity interval training (HIIT) along …

Tea polyphenols ameliorates memory decline in aging model rats by inhibiting brain TLR4/NF-κB inflammatory signaling pathway caused by intestinal flora dysbiosis

C Song, Y Zhang, L Cheng, M Shi, X Li, L Zhang… - Experimental …, 2021 - Elsevier
Aims Tea is a rich source of pharmacologically active molecules that has been suggested to
provide a variety of health benefits. However, its mechanism of action in aging-related …

Neuromodulating roles of estrogen and phytoestrogens in cognitive therapeutics through epigenetic modifications during aging

P Singh, V Paramanik - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Estrogen (E2) plays important role in regulating hippocampal learning and memory. The
decline of E2 after menopause affects learning and memory and increases the risk of …

Improvement of cognitive function in ovariectomized rats by human neural stem cells overexpressing choline acetyltransferase via secretion of NGF and BDNF

EJ Yoon, Y Choi, D Park - International journal of molecular sciences, 2022 - mdpi.com
Menopause is associated with memory deficits attributed to reduced serum estrogen levels.
We evaluated whether an increase in brain-derived neurotrophic factor (BDNF) and nerve …

Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of …

R Yakhkeshi, F Roshani, K Akhoundzadeh… - Physiology & Behavior, 2022 - Elsevier
There is a sex difference in vulnerability to PTSD and in response to therapeutic
interventions. Since relation between gonadal hormones and PTSD has been revealed, this …