Neurodevelopmental programming—the implementation of the genetic and epigenetic
blueprints that guide and coordinate normal brain development—requires tight regulation of …

Human brain development is influenced by early-life experiences, particularly during
sensitive periods, with impact on cognitive and emotional outcomes. Understanding how the …

A key obstacle to understanding neural circuits in the cerebral cortex is that of unraveling the
diversity of GABAergic interneurons. This diversity poses general questions for neural circuit …

Childhood trauma and neglect influence emotional development and increase the risk for
and severity of mental illness. Women have a heightened susceptibility to the effects of early …

This paper integrates the cumulative stress hypothesis with the mismatch hypothesis, taking
into account individual differences in sensitivity to programming. According to the cumulative …

The prenatal and postnatal early-life periods are both dynamic and vulnerable windows for
brain development. During these important neurodevelopmental phases, essential …

ABSTRACT A close association between early‐life experience and cognitive and emotional
outcomes is found in humans. In experimental models, early‐life experience can directly …

Maternal sensory signals in early life play a crucial role in programming the structure and
function of the developing brain, promoting vulnerability or resilience to emotional and …

Experiences during early development profoundly affect development of the central nervous
system (CNS) to impart either risk for or resilience to later psychopathology. Work in the …

Environmental enrichment (EE) was shown recently to accelerate brain development in
rodents. Increased levels of maternal care, and particularly tactile stimulation through licking …