The construction of heterocyclic compounds from activated cyclopropane derivatives offers
an alternative strategy for the preparation of molecules that may be of interest from a …

Covering: up to August 2015 Alkaloids account for some of the most beautiful and
biologically active natural products. Although they are usually classified along biosynthetic …

The amide bond is one of the most important functional groups in chemistry and biology. 1
Due to the strong resonance interaction between nN and π* C O orbitals (Figure 1), 2 the …

Catalysis and synthesis are intimately linked in modern organic chemistry. The synthesis of
complex molecules is an ever evolving area of science. In many regards, the inherent …

Mn (III)-mediated formal [3+ 3]-annulation has been developed using readily available vinyl
azides and cyclopropanols with a wide range of substituents. Vinyl azides were successfully …

The main objective of this review is to provide a comprehensive survey of methods used for
stereoselective construction of carbon–nitrogen bonds during the total synthesis of nitrogen …

Among the fundamental chemical transformations in organic synthesis, the [3, 3]-sigmatropic
rearrangement occupies a unique position as a powerful, reliable, and well-defined method …

Nucleophilic addition to amides has been recognized as a promising transformation for total
synthesis of complex alkaloids. Amides can accept two different organometallic reagents …

We report a common strategy to facilitate the syntheses of the polycyclic alkaloids (−)‐
FR901483 (1) and (+)‐TAN1251C (2). A divergent synthetic strategy provides access to both …

The Mannich reaction has been widely used to effectively construct C–N and C–C bonds in
organic synthesis. This review focuses on selected applications of the intramolecular …