Effect of exosomal miRNA on cancer biology and clinical applications

Z Sun, K Shi, S Yang, J Liu, Q Zhou, G Wang, J Song… - Molecular cancer, 2018 - Springer
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …

A glimpse of the mechanisms related to renal fibrosis in diabetic nephropathy

LF Zeng, Y Xiao, L Sun - Renal Fibrosis: Mechanisms and Therapies, 2019 - Springer
Diabetic nephropathy (DN) is a common kidney disease in people with diabetes, which is
also a serious microvascular complication of diabetes and the main cause of end-stage …

Differential expression of urinary exosomal microRNAs miR-21-5p and miR-30b-5p in individuals with diabetic kidney disease

J Zang, AP Maxwell, DA Simpson, GJ McKay - Scientific reports, 2019 - nature.com
Biomarkers for the identification of diabetic kidney disease (DKD) are needed as current
tests lack sensitivity for detecting early kidney damage. MicroRNAs (miRNAs) are short, non …

microRNA crosstalk influences epithelial-to-mesenchymal, endothelial-to-mesenchymal, and macrophage-to-mesenchymal transitions in the kidney

SP Srivastava, AF Hedayat, K Kanasaki… - Frontiers in …, 2019 - frontiersin.org
microRNAs (miRNAs) are small, non-coding nucleotides that regulate diverse biological
processes. Altered microRNA biosynthesis or regulation contributes to pathological …

Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of kidney fibrosis in diabetic nephropathy

F Conserva, M Barozzino, F Pesce, C Divella… - Scientific reports, 2019 - nature.com
Diabetic Nephropathy (DN) is a chronic complication of diabetes and the primary cause of
end stage renal disease. Differential diagnosis for DN requires invasive histological …

MicroRNA-21: A critical pathogenic factor of diabetic nephropathy

S Liu, W Wu, J Liao, F Tang, G Gao, J Peng… - Frontiers in …, 2022 - frontiersin.org
Diabetic nephropathy (DN), one of the most common and intractable microvascular
complications of diabetes, is the main cause of terminal renal disease globally. MicroRNA …

Long noncoding RNA MIAT regulates primary human retinal pericyte pyroptosis by modulating miR-342–3p targeting of CASP1 in diabetic retinopathy

X Yu, X Ma, W Lin, Q Xu, H Zhou, HY Kuang - Experimental eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is the leading cause of visual impairment and acquired blindness
among adults worldwide. Retinal microvascular pericyte deficiency is one of the earliest …

miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6

ZH Jiang, YZ Tang, HN Song… - International …, 2020 - spandidos-publications.com
Diabetic kidney disease (DKD) is one of the major microvascular complications in patients
with type 1 and/or type 2 diabetes, the first cause of end‑stage renal disease (ESRD) in …

Micro-RNA implications in type-1 diabetes mellitus: a review of literature

K Margaritis, G Margioula-Siarkou, S Giza… - International journal of …, 2021 - mdpi.com
Type-1 diabetes mellitus (T1DM) is one of the most well-defined and complex metabolic
disorders, characterized by hyperglycemia, with a constantly increasing incidence in …

High glucose induces mesangial cell apoptosis through miR-15b-5p and promotes diabetic nephropathy by extracellular vesicle delivery

YC Tsai, MC Kuo, WW Hung, LY Wu, PH Wu… - Molecular Therapy, 2020 - cell.com
Diabetic nephropathy (DN) is an increasing threat to human health and is regarded as an
important public issue. The pathophysiologic mechanisms of DN are complicated. The …