Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Mechanical cues are crucial for survival, adaptation, and normal homeostasis in virtually
every cell type. The transduction of mechanical messages into intracellular biochemical …

The use of repurposing drugs that may have neoplastic and anticancer effects increases the
efficiency and decrease resistance to chemotherapy drugs through a biochemical and …

The vertebrate intestine experiences a range of intrinsically generated and external forces
during both development and adult homeostasis. It is increasingly understood how the …

Mechanical features of cancer cells emerge as a distinct trait during development and
progression of solid tumors. Herein, we discuss recent key findings regarding the impact of …

The tumor microenvironment (TME) is crucial in cancer progression, and the extracellular
matrix (ECM) is an important TME component. Collagen is a major ECM component that …

Epithelial cell divisions are coordinated with cell loss to preserve epithelial integrity.
However, how epithelia adapt their rate of cell division to changes in cell number, for …

Skin and its cell components continuously subject to extrinsic and intrinsic mechanical
forces and are mechanical sensitive. Disturbed mechanical homeostasis may lead to …

Mechanistic target of rapamycin (mTOR) is a central signaling hub that integrates networks
of nutrient availability, cellular metabolism, and autophagy in eukaryotic cells. mTOR kinase …

Energy‐sensing in viscoelastic substrates has recently been shown to be an important
regulator of cellular activities, modulating mechanical transmission and transduction …