C− C bond-forming lyases in organic synthesis
M Brovetto, D Gamenara, P Saenz Mendez… - Chemical …, 2011 - ACS Publications
Lyases are enzymes that catalyze the bond construction and breaking by means other than
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …
Thiamin diphosphate catalysis: enzymic and nonenzymic covalent intermediates
R Kluger, K Tittmann - Chemical reviews, 2008 - ACS Publications
The idea of “reasonableness” of organic reactions is based on recorded evidence of
reaction patterns. The logical patterns are organized based on structural and functional …
reaction patterns. The logical patterns are organized based on structural and functional …
Synthetic biology and metabolic engineering approaches to produce biofuels
CA Rabinovitch-Deere, JWK Oliver… - Chemical …, 2013 - ACS Publications
Fossil fuels (crude oil, coal, and natural gas) represent the current primary source of the
world's energy supply, accounting for 87% of global energy. 1 World energy consumption is …
world's energy supply, accounting for 87% of global energy. 1 World energy consumption is …
Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions
F Jordan - Natural product reports, 2003 - pubs.rsc.org
Covering: 1990–2002The mechanism of thiamin diphosphate-dependent enzymatic
reactions is discussed, concentrating on two enzymes involved in decarboxylating pyruvic …
reactions is discussed, concentrating on two enzymes involved in decarboxylating pyruvic …
Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2‐Hydroxy Ketones
The thiamin diphosphate‐and Mg2+‐dependent enzyme benzoylformate decarboxylase
(BFD) from Pseudomonas putida was characterized with respect to its suitability to catalyze …
(BFD) from Pseudomonas putida was characterized with respect to its suitability to catalyze …
The Crystal Structure of Benzoylformate Decarboxylase at 1.6 Å Resolution: Diversity of Catalytic Residues in Thiamin Diphosphate-Dependent Enzymes,
MS Hasson, A Muscate, MJ McLeish… - Biochemistry, 1998 - ACS Publications
The crystal structure of the thiamin diphosphate (ThDP)-dependent enzyme benzoylformate
decarboxylase (BFD), the third enzyme in the mandelate pathway of Pseudomonas putida …
decarboxylase (BFD), the third enzyme in the mandelate pathway of Pseudomonas putida …
Characterization of Phenylpyruvate Decarboxylase, Involved in Auxin Production of Azospirillum brasilense
Azospirillum brasilense belongs to the plant growth-promoting rhizobacteria with direct
growth promotion through the production of the phytohormone indole-3-acetic acid (IAA). A …
growth promotion through the production of the phytohormone indole-3-acetic acid (IAA). A …
Synthetic potential of thiamin diphosphate-dependent enzymes
GA Sprenger, M Pohl - Journal of Molecular Catalysis B: Enzymatic, 1999 - Elsevier
Thiamin diphosphate-dependent enzymes (mainly pyruvate decarboxylase, transketolase,
benzoylformate decarboxylase) are increasingly being used to perform regio-and …
benzoylformate decarboxylase) are increasingly being used to perform regio-and …
Application of α-keto acid decarboxylases in biotransformations
The advantages of using enzymes in the synthesis of organic compounds relate to their
versatility, high reaction rates, and regio-and stereospecificity and the relatively mild reaction …
versatility, high reaction rates, and regio-and stereospecificity and the relatively mild reaction …
Benzaldehyde lyase, a novel thiamine PPi-requiring enzyme, from Pseudomonas fluorescens biovar I
B González, R Vicuña - Journal of bacteriology, 1989 - Am Soc Microbiol
Pseudomonas fluorescens biovar I can grow on benzoin as the sole carbon and energy
source. This ability is due to benzaldehyde lyase, a new type of enzyme that irreversibly …
source. This ability is due to benzaldehyde lyase, a new type of enzyme that irreversibly …