Concise review: mind the gap: challenges in characterizing and quantifying cell-and tissue-based therapies for clinical translation

EA Rayment, DJ Williams - Stem Cells, 2010 - academic.oup.com
There are many challenges associated with characterizing and quantifying cells for use in
cell-and tissue-based therapies. From a regulatory perspective, these advanced treatments …

RNA-based tools for nuclear reprogramming and lineage-conversion: towards clinical applications

JA Bernal - Journal of cardiovascular translational research, 2013 - Springer
The therapeutic potential of induced pluripotent stem cells (iPSCs) is well established.
Safety concerns remain, however, and these have driven considerable efforts aimed at …

The ethos and ethics of translational research

J Maienschein, M Sunderland, RA Ankeny… - The American Journal …, 2008 - Taylor & Francis
Calls for the “translation” of research from bench to bedside are increasingly demanding.
What is translation, and why does it matter? We sketch the recent history of outcome …

The stem cell debate continues: the buying and selling of eggs for research

F Baylis, C McLeod - Journal of Medical Ethics, 2007 - jme.bmj.com
Now that stem cell scientists are clamouring for human eggs for cloning-based stem cell
research, there is vigorous debate about the ethics of paying women for their eggs …

Ethical challenges of germline genetic enhancement

I Macpherson, MV Roqué, I Segarra - Frontiers in Genetics, 2019 - frontiersin.org
The new reproductive technologies have opened the door to different processes of germline
genetic enhancement by which the characteristics of an individual according to the interests …

Enculturating cells: The anthropology, substance, and science of stem cells

A Bharadwaj - Annual Review of Anthropology, 2012 - annualreviews.org
The ongoing enculturation of stem cells with culturally specific meaning in different global
locales is receiving critical anthropological attention. As an anthropological subject and …

Examining the ethical and social issues of health technology design through the public appraisal of prospective scenarios: a study protocol describing a multimedia …

P Lehoux, P Gauthier, B Williams-Jones, FA Miller… - Implementation …, 2014 - Springer
Background The design of health technologies relies on assumptions that affect how they
will be implemented, such as intended use, complexity, impact on user autonomy, and …

Personal stem cell banking and the problem with property

M Fannin - Social & Cultural Geography, 2011 - Taylor & Francis
Social scientists increasingly view biotechnological innovation as inseparable from the
social and economic transformations of value attributed to human tissue. Informed by …

Insights into bone marrow‐derived mesenchymal stem cells safety for cutaneous repair and regeneration

Y Wu, S Huang, J Enhe, X Fu - International wound journal, 2012 - Wiley Online Library
Wound healing involves the orchestration of a complex process of interactions between
numerous types of cell, components of extracellular matrix and signalling molecules …

You are our only hope”: Trading metaphorical “magic bullets” for stem cell “superheroes

L Burns - Theoretical medicine and bioethics, 2009 - Springer
In the wake of two recent developments in stem cell research, it is a fitting time to reassess
the claim that stem cells will radically transform the concept and function of medicine. The …