Cancer-associated venous thromboembolism

AA Khorana, N Mackman, A Falanga… - Nature reviews Disease …, 2022 - nature.com
Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Cancer-associated thrombosis: an overview of mechanisms, risk factors, and treatment

NB Abdol Razak, G Jones, M Bhandari, MC Berndt… - Cancers, 2018 - mdpi.com
Cancer-associated thrombosis is a major cause of mortality in cancer patients, the most
common type being venous thromboembolism (VTE). Several risk factors for developing …

Understanding the extracellular vesicle surface for clinical molecular biology

S Hallal, Á Tűzesi, GE Grau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …

Cancer-associated venous thromboembolism: burden, mechanisms, and management

C Ay, I Pabinger, AT Cohen - Thrombosis and haemostasis, 2017 - thieme-connect.com
Venous thromboembolism (VTE) is a significant health problem in the general population
but especially in cancer patients. In this review, we discuss the epidemiology and burden of …

Cancer-associated pathways and biomarkers of venous thrombosis

Y Hisada, N Mackman - Blood, The Journal of the American …, 2017 - ashpublications.org
Cancer patients have an increased risk of venous thromboembolism (VTE). In this review,
we summarize common and cancer type–specific pathways of VTE in cancer patients …

Molecular interactions at the surface of extracellular vesicles

EI Buzás, EÁ Tóth, BW Sódar… - Seminars in …, 2018 - Springer
Extracellular vesicles such as exosomes, microvesicles, apoptotic bodies, and large
oncosomes have been shown to participate in a wide variety of biological processes and are …

Single-step isolation of extracellular vesicles by size-exclusion chromatography

AN Böing, E Van Der Pol, AE Grootemaat… - Journal of …, 2014 - Taylor & Francis
Background Isolation of extracellular vesicles from plasma is a challenge due to the
presence of proteins and lipoproteins. Isolation of vesicles using differential centrifugation or …

Platelets and extracellular vesicles and their cross talk with cancer

S Lazar, LE Goldfinger - Blood, The Journal of the American …, 2021 - ashpublications.org
Platelets play significant and varied roles in cancer progression, as detailed throughout this
review series, via direct interactions with cancer cells and by long-range indirect interactions …

Epidemiology of cancer-associated venous thrombosis

JF Timp, SK Braekkan, HH Versteeg… - Blood, The Journal …, 2013 - ashpublications.org
Cancer-associated venous thrombosis is a common condition, although the reported
incidence varies widely between studies depending on patient population, start and duration …

Classification, functions, and clinical relevance of extracellular vesicles

E Van der Pol, AN Böing, P Harrison, A Sturk… - Pharmacological …, 2012 - Elsevier
Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …