Molecular docking is the most frequently used computational method for studying the
interactions between organic molecules and biological macromolecules. In this context …

The angiotensin-converting enzyme (ACE) is a two-domain dipeptidylcarboxypeptidase,
which has a direct involvement in the control of blood pressure by performing the hydrolysis …

Molecular docking is a computational chemistry method which has become essential for the
rational drug design process. In this context, it has had great impact as a successful tool for …

Jasmonates are phytohormones that regulate defense and developmental processes in land
plants. Despite the chemical diversity of jasmonate ligands in different plant lineages, they …

Jasmonates are fatty acid derivatives that control several plant processes including growth,
development and defense. Despite the chemical diversity of jasmonates, only jasmonoyl-L …

Pancreatic cancer is the eleventh most common cancer type and the seventh leading cause
of cancer mortality globally. Although chemotherapy is widely employed in the treatment of …

Abstract Janus kinase 3 (JAK3) is a promising drug target for the treatment of inflammatory
diseases, autoimmune disorders, organ transplant rejection and various cancers. In the …

Abstract Sulfonic acid functionalized 1, 4-diazabicyclo [2.2. 2] octane supported on Merrifield
resin,[MerDABCO-SO 3 H] Cl catalyst was prepared and explored in one-pot four …

Substituted amino-piperazine derivatives were synthesized and used as precursors for the
preparation of a series of new organometallic Re (I) imine complexes with the general …

Thermolysin is a bacterial proteolytic enzyme, considered by many authors as a
pharmacological and biological model of other mammalian enzymes, with similar structural …