Age-related macular degeneration (AMD) is the leading cause of visual impairment in the
aging population with limited understanding of its pathogenesis and a lack of effective …

Vitamin A is an essential fat-soluble vitamin that occurs in various chemical forms. It is
essential for several physiological processes. Either hyper-or hypovitaminosis can be …

The complement system is a part of the immune system and consists of multiple complement
components with biological functions such as defense against pathogens and …

There are currently no treatments for geographic atrophy, the advanced form of age-related
macular degeneration. Hence, innovative studies are needed to model this condition and …

Age-related macular degeneration (AMD) is the leading cause of vision loss and visual
impairment in people over 50 years of age. In the current therapeutic landscape, intravitreal …

The complement system is involved in the pathogenesis of several ocular diseases,
providing a rationale for the investigation of complement-targeting therapeutics for these …

Introduction Intravitreal anti-vascular endothelial growth factor (VEGF) injections for
exudative age-related macular degeneration (eAMD) are effective and safe but require …

Despite being the most prevalent cause of inherited blindness in children, Stargardt disease
is yet to achieve the same clinical trial success as has been achieved for other inherited …

Age‐related macular degeneration (AMD) is a multifactorial disease, which can culminate in
irreversible vision loss and blindness in elderly. Nowadays, there is a big gap between dry …

Given the expanding elderly population in the United States and the world, it is important to
understand the processes underlying both natural and pathological age-related changes in …