S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …

In humans, the S100 protein family is composed of 21 members that exhibit a high degree of
structural similarity, but are not functionally interchangeable. This family of proteins …

S100, a multigenic family of non‐ubiquitous Ca2+‐modulated proteins of the EF‐hand type
expressed in vertebrates exclusively, has been implicated in intracellular and extracellular …

S100B is a calcium‐binding peptide produced mainly by astrocytes that exert paracrine and
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …

The S100 proteins comprise at least 25 members, forming the largest group of EF-hand
signalling proteins in humans. Although the proteins are expressed in many tissues, each …

J. Neurochem.(2012) 120, 644–659. Abstract S100B is a calcium‐binding protein
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …

S100 protein family has been implicated in multiple stages of tumorigenesis and
progression. Among the S100 genes, 22 are clustered at chromosome locus 1q21, a region …

The transition from benign tumor growth to malignancy is manifested by the ability of tumor
cells to traverse tissue barriers and invade surrounding tissues. The traversal of basement …

In recent years there has been a proliferation of interest in the brain‐specific protein S100B,
its many physiologic roles, and its behaviour in various neuropathologic conditions. Since …

Polo-like kinase 1 (Plk1) has an important role in the regulation of M phase of the cell cycle.
In addition to its cell cycle-regulatory function, Plk1 has a potential role in tumorigenesis …