Oxidative cyclization in natural product biosynthesis

MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

The biosynthetic logic of polyketide diversity

C Hertweck - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Abstract Molecular Lego: Polyketides represent a highly diverse group of natural products
with structurally intriguing carbon skeletons (see picture) which are assembled from simple …

SpecDis: Quantifying the comparison of calculated and experimental electronic circular dichroism spectra

T Bruhn, ANU Schaumlöffel, Y Hemberger… - Chirality, 2013 - Wiley Online Library
This article outlines theory and practice of the comparison of calculated and experimental
electronic circular dichroism (ECD) curves to determine the absolute configuration of chiral …

Flavoenzymes: versatile catalysts in biosynthetic pathways

CT Walsh, TA Wencewicz - Natural product reports, 2013 - pubs.rsc.org
Covering: up to the end of May 2012 Riboflavin-based coenzymes, tightly bound to enzymes
catalyzing substrate oxidations and reductions, enable an enormous range of chemical …

Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function

JD Rudolf, CY Chang, M Ma, B Shen - Natural Product Reports, 2017 - pubs.rsc.org
Covering: up to January 2017 Cytochrome P450 enzymes (P450s) are some of the most
exquisite and versatile biocatalysts found in nature. In addition to their well-known roles in …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2011 - pubs.rsc.org
Covering: 2009. Previous review: Nat. Prod. Rep., 2010, 27, 165 This review covers the
literature published in 2009 for marine natural products, with 857 citations (588 for the …

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

C Olano, C Méndez, JA Salas - Natural product reports, 2010 - pubs.rsc.org
Covering: 2002 to September 2009 In recent years, a number of gene clusters involved in
the biosynthesis of polyketide compounds have been characterized and the genes have …

Isolation, biological activity and synthesis of benzannulated spiroketal natural products

J Sperry, ZE Wilson, DCK Rathwell… - Natural Product …, 2010 - pubs.rsc.org
Isolation, biological activity and synthesis of benzannulated spiroketal natural products -
Natural Product Reports (RSC Publishing) DOI:10.1039/B911514P Royal Society of Chemistry …

Die biosynthetische Grundlage der Polyketid‐Vielfalt

C Hertweck - Angewandte Chemie, 2009 - Wiley Online Library
Abstract Molekulares Lego: Polyketide bilden eine äußerst vielfältige Gruppe von
Naturstoffen mit faszinierenden Kohlenstoffgerüsten (siehe Beispiele), die aus einfachen …

Chemistry and biosynthesis of bacterial polycyclic xanthone natural products

L Kong, Z Deng, D You - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to the end of 2021 Bacterial polycyclic xanthone natural products (BPXNPs)
are a growing family of natural xanthones featuring a pentangular architecture with various …