Modern omics technologies can generate massive amounts of biomedical data, providing
unprecedented opportunities for individualized precision medicine. However, traditional …

Objective In recent years, the utilization of indocyanine green near-infrared (ICG NIR) light
imaging-guided lymph node dissection in the context of minimally invasive radical gastric …

Objective Bile reflux plays a key role in the development of gastric intestinal metaplasia
(GIM), an independent risk factor of gastric cancer. Here, we aimed to explore the biological …

Background Epidemiological evidence suggests an association between lifestyle habits
(smoking, alcohol consumption, tea, coffee intake, etc.) and gastric cancer (GC). However …

Gastric cancer (GC) is a prevalent form of cancer, with Helicobacter pylori (H. pylori)
infection being the most common risk factor. Recent studies have highlighted the role of long …

Background Elevated PPP4C expression has been associated with poor prognostic
implications for patients suffering from lung adenocarcinoma (LUAD). The extent to which …

Background Monocytes play a critical role in tumor initiation and progression, with their
impact on prostate adenocarcinoma (PRAD) not yet fully understood. This study aimed to …

Overcoming the immunosuppressive tumor microenvironment and identifying widely used
immunosuppressants with minimal side effects are two major challenges currently …

As a large and structurally diverse family of small molecules, bile acids play a crucial role in
regulating lipid, glucose, and energy metabolism. In the human body, bile acids share a …

Background Abnormal sphingolipid metabolism (SM) is closely linked to the incidence of
cancers. However, the role of SM in pancreatic cancer (PC) remains unclear. This study …