In natural habitats, microbes form multispecies communities that commonly face rapidly
changing and highly competitive environments. Thus, phenotypic heterogeneity has evolved …

Phenotypic plasticity of microbial cells has attracted much attention and several research
efforts have been dedicated to the description of methods aiming at characterizing …

Cell‐to‐cell heterogeneity typically evolves due to a manifold of biological and
environmental factors and special phenotypes are often relevant for the fate of the whole …

Conventional propidium iodide (PI) staining requires the execution of multiple steps prior to
analysis, potentially affecting assay results as well as cell vitality. In this study, this multistep …

Background Microfluidic lab-on-chip technology combined with live-cell imaging has
enabled the observation of single cells in their spatio-temporal context. The mother machine …

Periodic forcing of nonlinear oscillators leads to a large number of dynamic behaviors. The
coupling of the cell cycle to the circadian clock provides a biological realization of such …

A microfluidic device for microbial single-cell cultivation of bacteria was modeled and
simulated using COMSOL Multiphysics. The liquid velocity field and the mass transfer within …

The development of mini-and micro-cultivation devices allows the optimization of
bioprocesses to be speeded up, as well as a better understanding of microbial physiology …

Phase contrast microscopy cannot give sufficient information on bacterial metabolic activity,
or if a cell is dead, it has the fate to die or it is in a viable but non-growing state. Thus, a …

Microfluidic single‐cell bioreactors have found widespread application to investigate growth
and gene expression of microbial model organisms, but yet there are few attempts to …