Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?

MH Kazemi, M Sadri, A Najafi, A Rahimi… - Frontiers in …, 2022 - frontiersin.org
Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are
recruited into the tumor site to fight against tumors. However, their small number and …

Vaccines in breast cancer: challenges and breakthroughs

GN Fatima, H Fatma, SK Saraf - Diagnostics, 2023 - mdpi.com
Breast cancer is a problem for women's health globally. Early detection techniques come in
a variety of forms ranging from local to systemic and from non-invasive to invasive. The …

Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …

AKMH Morshed, S Al Azad, MAR Mia, MF Uddin… - Molecular Diversity, 2023 - Springer
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …

Multiplex immunofluorescence and the digital image analysis workflow for evaluation of the tumor immune environment in translational research

F Rojas, S Hernandez, R Lazcano… - Frontiers in …, 2022 - frontiersin.org
A robust understanding of the tumor immune environment has important implications for
cancer diagnosis, prognosis, research, and immunotherapy. Traditionally …

Nanomedicine-based drug-targeting in breast cancer: pharmacokinetics, clinical progress, and challenges

M Rahman, O Afzal, SNMN Ullah, MY Alshahrani… - ACS …, 2023 - ACS Publications
Breast cancer (BC) is a malignant neoplasm that begins in the breast tissue. After skin
cancer, BC is the second most common type of cancer in women. At the end of 2040, the …

Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Current progress and challenges of immunotherapy in gastric cancer: A focus on CAR-T cells therapeutic approach

M Entezam, MJ Sanaei, Y Mirzaei, AH Mer… - Life sciences, 2023 - Elsevier
Gastric cancer (GC) is a severe malignancy, accounting for the third most common cancer
death worldwide. Despite the development of chemo-radiation therapy, there has not been …

Immunostimulatory properties of chemotherapy in breast cancer: From immunogenic modulation mechanisms to clinical practice

J Zhang, S Pan, C Jian, L Hao, J Dong, Q Sun… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) is the most common malignancy among females. Chemotherapy drugs
remain the cornerstone of treatment of BC and undergo significant shifts over the past 100 …

Advances in immunotherapy for breast cancer and feline mammary carcinoma: From molecular basis to novel therapeutic targets

T Vilela, S Valente, J Correia, F Ferreira - Biochimica et Biophysica Acta …, 2024 - Elsevier
The role of inflammation in cancer is a topic that has been investigated for many years. As
established, inflammation emerges as a defining characteristic of cancer, presenting itself as …

Clinical impact of PD-L1 expression in triple-negative breast cancer patients with residual tumor burden after neoadjuvant chemotherapy

G Oner, S Önder, H Karatay, N Ak, M Tükenmez… - World Journal of …, 2021 - Springer
Abstract Background Studies on PD-L1 expression in breast cancer have gained importance
in recent years, especially in triple-negative breast cancer (TNBC). Our aim was to analyze …