Pathophysiology of age-related macular degeneration: implications for treatment
J Garcia-Garcia, R Usategui-Martin, MR Sanabria… - Ophthalmic …, 2022 - karger.com
Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal
disease that affects millions of people worldwide and has become the leading cause of …
disease that affects millions of people worldwide and has become the leading cause of …
[HTML][HTML] Molecular pathogenesis of subretinal fibrosis in neovascular AMD focusing on epithelial-mesenchymal transformation of retinal pigment epithelium
Age-related macular degeneration (AMD) is a leading cause of vision loss among elderly
people in developed countries. Neovascular AMD (nAMD) accounts for more than 90% of …
people in developed countries. Neovascular AMD (nAMD) accounts for more than 90% of …
[HTML][HTML] Mechanistic insight into age-related macular degeneration (AMD): anatomy, epidemiology, genetics, pathogenesis, prevention, implications, and treatment …
MA Amini, A Karbasi, M Vahabirad… - Chonnam Medical …, 2023 - ncbi.nlm.nih.gov
One of the most complicated eye disorders is age-related macular degeneration (AMD)
which is the leading cause of irremediable blindness all over the world in the elderly. AMD is …
which is the leading cause of irremediable blindness all over the world in the elderly. AMD is …
Mechanism of circular RNA-mediated regulation of L-DOPA to improve wet age-related macular degeneration
X Jia, Y Sun, T Wang, L Zhong, J Deng, X Zhu - Gene, 2023 - Elsevier
This study aimed to investigate the effect and mechanism of levodopa (L-DOPA) in the
treatment of age-related macular degeneration (AMD). A wet AMD cell model was created …
treatment of age-related macular degeneration (AMD). A wet AMD cell model was created …
Role of adrenomedullin 2/intermedin in the pathogenesis of neovascular age-related macular degeneration
S Kakihara, Y Matsuda, K Hirabayashi, A Imai… - Laboratory …, 2023 - Elsevier
Abstract Adrenomedullin 2 (AM2; also known as intermedin) is a member of the
adrenomedullin (AM) peptide family. Similarly to AM, AM2 partakes in a variety of …
adrenomedullin (AM) peptide family. Similarly to AM, AM2 partakes in a variety of …
The transcriptome profile of RPE cells by the fullerenol against hydrogen peroxide stress
X Wu, F Yao, JY Xu, J Chen, Y Lu, W Li, J Deng… - Frontiers in …, 2022 - frontiersin.org
Age-related macular degeneration (AMD) causes central vision impairment with increased
incidence. In the pathogenesis of AMD, reactive oxygen species (ROS) are associated with …
incidence. In the pathogenesis of AMD, reactive oxygen species (ROS) are associated with …
Subretinal fibrosis secondary to neovascular age-related macular degeneration: mechanisms and potential therapeutic targets
J Zhang, X Sheng, Q Ding, Y Wang… - Neural Regeneration …, 2025 - journals.lww.com
Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular
degeneration. It causes local damage to photoreceptors, retinal pigment epithelium, and …
degeneration. It causes local damage to photoreceptors, retinal pigment epithelium, and …
Adrenomedullin ameliorates pulmonary fibrosis by regulating TGF-ß-Smads signaling and myofibroblast differentiation
Y Wei, M Tanaka, T Sakurai, A Kamiyoshi… - …, 2021 - academic.oup.com
Pulmonary fibrosis is an irreversible, potentially fatal disease. Adrenomedullin (AM) is a
multifunctional peptide whose activity is regulated by receptor activity-modifying protein 2 …
multifunctional peptide whose activity is regulated by receptor activity-modifying protein 2 …
[PDF][PDF] Physiological Angiogenesis in Neonates
OIR Model - soar-ir.repo.nii.ac.jp
On postnatal day 7 (P7), the mice were euthanized by cervical dislocation, their eyes were
removed, and flat mounted retinal specimens were prepared. They were stained with …
removed, and flat mounted retinal specimens were prepared. They were stained with …