In 1949 Polge, Parks and Smith1 reported on the “chance” discovery of glycerol's
cryoprotective function during their efforts to preserve avian spermatozoa in the frozen state …

Millions of biological samples are currently kept at low tempertures in cryobanks/
biorepositories for long-term storage. The quality of the biospecimen when thawed …

Coronary heart disease (CHD) and depression are very common and often co-existing
disorders. In addition to psychological and social morbidity, depression exacerbates …

Human embryonic stem (hES) cells have enormous potential for clinical applications.
However, one major challenge is to achieve high cell recovery rate after cryopreservation …

Millions of biological samples, including cells of human, animal or bacterial origin, viruses,
serum/plasma or DNA/RNA, are stored every year throughout the world for diagnostics and …

The ability to analyze cryopreserved peripheral blood mononuclear cell (PBMC) from
biobanks for antigen-specific immunity is necessary to evaluate response to immune-based …

Mechanisms by which the resin monomer 2-hydroxyethyl methacrylate (HEMA) induces
hypersensitivity reactions in humans are not well-established, nor have the direct effects of …

Although cryopreservation of peripheral blood mononuclear cells (PBMC) is a commonly
used technique, the degree to which it affects subsequent functional studies has not been …

The development and use of complex cell-based products in clinical and discovery science
continues to grow at an unprecedented pace. To this end, cryopreservation plays a critical …

Natural deep eutectic systems (NADES) are emerging as potential cryoprotective agents
(CPA) for cell preservation. In this investigation, we develop an optimized CPA formulation …