The lifelong health of an individual is shaped during critical periods of development. The
fetus is particularly susceptible to internal and external stimuli, many of which can alter …

The worldwide obesity epidemic has been mainly attributed to lifestyle changes. However,
who becomes obese in an obesity-prone environment is largely determined by genetic …

Obesity, the epidemic of the 21st century, carries a markedly increased risk for comorbid
complications, such as type 2 diabetes, cancer, hypertension, dyslipidemia, cardiovascular …

Modern lifestyle, genetics, nutritional overload through high-fat diet attributed prevalence
and diabetes outcomes with various complications primarily due to obesity in which energy …

Although DNA methylation is now recognized as an important mediator of complex
diseases, the extent to which the genetic basis of such diseases is accounted for by DNA …

Background: Maternal obesity has adverse effects on oocyte quality, embryo development,
and the health of the offspring. Objectives: To understand the underlying mechanisms …

Epigenetic inheritance plays a crucial role in many biological processes, such as gene
expression in early embryo development, imprinting and the silencing of transposons. It has …

As the very low-calorie ketogenic diet (VLCKD) gains increased interest as a therapeutic
approach for many diseases, little is known about its therapeutic use in childhood obesity …

We previously showed that paternal high‐fat diet (HFD) consumption programs β‐cell
dysfunction in female rat offspring, together with transcriptome alterations in islets. Here we …

Obesity is a major health issue in the developed nations, and it has been increasingly clear
that both genetics and environment play an important role in determining if an individual will …