The interaction between microglia and astrocytes exhibits a relatively balanced state in
order to maintain homeostasis in the healthy central nervous system (CNS). Disease stimuli …

Glial cells in the central nervous system (CNS) are composed of oligodendrocytes,
astrocytes and microglia. They contribute more than half of the total cells of the CNS, and are …

The thalamus plays a central coordinating role in the brain. Thalamic neurons are organized
into spatially distinct nuclei, but the molecular architecture of thalamic development is poorly …

Late prenatal development of the human neocortex encompasses a critical period of
gliogenesis and cortical expansion. However, systematic single-cell analyses to resolve …

The vision of astroglia as a bare scaffold to neuronal circuitry has been largely overturned.
Astrocytes exert a neurotrophic function, but also take active part in supporting synaptic …

An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

The cerebral cortex forms early in development according to a series of heritable
neurodevelopmental instructions. Despite deep evolutionary conservation of the cerebral …

The striatum is a central regulator of behavior and motor function through the actions of D1
and D2 medium-sized spiny neurons (MSNs), which arise from a common lateral ganglionic …

Recent studies have revealed the heterogeneous nature of astrocytes; however, how
diverse constituents of astrocyte-lineage cells are regulated in adult spinal cord after injury …

The development of the human neocortex is a highly dynamic process and involves complex
cellular trajectories controlled by cell-type-specific gene regulation1. Here, we collected …