Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Aggregation of specific proteins are histopathological hallmarks of several
neurodegenerative diseases, such as, Amyloid β (Aβ) plaques and tau neurofibrillary …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

Neurodegenerative diseases of the central nervous system progressively rob patients of
their memory, motor function, and ability to perform daily tasks. Advances in genetics and …

Abnormal aggregation of proteins into filamentous aggregates commonly associates with
many diseases, such as Alzheimer's disease, Parkinson's disease and type-2 diabetes …

Background There are currently no treatments that stop or slow the progression of
Parkinson's disease (PD). Case–control genome‐wide association studies have identified …

Studies have shown an overlap of Aβ plaques, tau tangles, and α-synuclein (α-syn)
pathologies in the brains of Alzheimer's disease (AD) and Parkinson's disease (PD) with …

An increasing number of cases where amyloids of different proteins are found in the same
patient are being reported. This observation complicates diagnosis and clinical intervention …

Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and
Huntington's disease currently affect tens of millions of people worldwide. Unfortunately, as …

Neuropathological diagnostic criteria of neurodegenerative disorders are based on the
presence of specific inclusions in a specific area of brain tissue that correlate with clinical …