Alcohol and the brain: neuronal molecular targets, synapses, and circuits

KP Abrahao, AG Salinas, DM Lovinger - Neuron, 2017 - cell.com
Ethanol is one of the most commonly abused drugs. Although environmental and genetic
factors contribute to the etiology of alcohol use disorders, it is ethanol's actions in the brain …

Alcohol use disorder: neurobiology and therapeutics

W Yang, R Singla, O Maheshwari, CJ Fontaine… - Biomedicines, 2022 - mdpi.com
Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits
involved in executive function leading to excessive consumption of alcohol, despite negative …

Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism

MW Meinhardt, S Pfarr, G Fouquet, C Rohleder… - Science …, 2021 - science.org
Alcohol-dependent patients commonly show impairments in executive functions that
facilitate craving and can lead to relapse. However, the molecular mechanisms leading to …

Single cell transcriptome profiling of the human alcohol-dependent brain

E Brenner, GR Tiwari, M Kapoor, Y Liu… - Human Molecular …, 2020 - academic.oup.com
Alcoholism remains a prevalent health concern throughout the world. Previous studies have
identified transcriptomic patterns in the brain associated with alcohol dependence in both …

Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies

J Calleja‐Conde, JA Morales‐García… - Addiction …, 2022 - Wiley Online Library
Classic psychedelics refer to substances such as lysergic acid diethylamide (LSD),
psilocybin, ayahuasca, and mescaline, which induce altered states of consciousness by …

Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence

F Alasmari, S Goodwani, RE McCullumsmith… - Progress in …, 2018 - Elsevier
Emerging evidence demonstrates that alcohol dependence is associated with dysregulation
of several neurotransmitters. Alterations in dopamine, glutamate and gamma-aminobutyric …

Neurobiology of alcohol seeking behavior

E Domi, A Domi, L Adermark, M Heilig… - Journal of …, 2021 - Wiley Online Library
Alcohol addiction is a chronic relapsing brain disease characterized by an impaired ability to
stop or control alcohol use despite adverse consequences. A main challenge of addiction …

Probiotics—role in alleviating the impact of alcohol liver disease and alcohol deaddiction: a systematic review

G Vidya Bernhardt, P Shivappa, J R. Pinto, R Ks… - Frontiers in …, 2024 - frontiersin.org
Background There are few efficient treatment options for alcohol addiction, which continues
to be a serious public health concern. The possible contribution of gut microbiota to the …

A critical review of methods and results in the search for genetic contributors to alcohol sensitivity

MA Schuckit - Alcoholism: Clinical and Experimental Research, 2018 - Wiley Online Library
Attributes of alcohol sensitivity are present before alcohol use disorders (AUD s) develop,
they predict those adverse alcohol outcomes, are familial in nature, and many are heritable …

Modeling aversion resistant alcohol intake in Indiana alcohol-preferring (P) rats

SN Katner, AM Sentir, KB Steagall, ZM Ding… - Brain Sciences, 2022 - mdpi.com
With the substantial social and medical burden of addiction, there is considerable interest in
understanding risk factors that increase the development of addiction. A key feature of …