Atherosclerosis in chronic kidney disease: more, less, or just different?

JM Valdivielso, D Rodríguez-Puyol… - … , and vascular biology, 2019 - Am Heart Assoc
Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …

Hyperphosphatemia and cardiovascular disease

C Zhou, Z Shi, N Ouyang, X Ruan - Frontiers in Cell and …, 2021 - frontiersin.org
Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range”
are highly associated with increased cardiovascular disease risk and mortality in the general …

FGF23 and phosphate–cardiovascular toxins in CKD

I Vogt, D Haffner, M Leifheit-Nestler - Toxins, 2019 - mdpi.com
Elevated levels of fibroblast growth factor 23 (FGF23) and phosphate are highly associated
with increased cardiovascular disease and mortality in patients suffering from chronic kidney …

A review of current evidence on the relationship between phosphate metabolism and metabolic syndrome

SK Wong - Nutrients, 2022 - mdpi.com
Phosphorus, present as phosphate in biological systems, is an essential mineral for various
biological activities and biochemical processes. Numerous studies have indicated that …

Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis

M Bozic, C Guzmán, M Benet, S Sánchez-Campos… - Journal of …, 2016 - Elsevier
Background & Aims The pathogenesis and progression of non-alcoholic fatty liver disease
(NAFLD) is still incompletely understood. Several nuclear receptors play a role in liver lipid …

A controlled increase in dietary phosphate elevates BP in healthy human subjects

J Mohammad, R Scanni, L Bestmann… - Journal of the …, 2018 - journals.lww.com
Background Despite epidemiologic evidence for increased cardiovascular morbidity and
mortality associated with both high dietary and serum phosphate in humans with normal …

Predictors of subclinical atheromatosis progression over 2 years in patients with different stages of CKD

M Gracia, A Betriu, M Martinez-Alonso… - Clinical Journal of the …, 2016 - journals.lww.com
Results Prevalence of atheromatosis was 68.7% and progressed in 59.8% of patients after
24 months. CKD progression was associated with atheromatosis progression, suggesting a …

Integrated assessment of pharmacological and nutritional cardiovascular risk management: blood pressure control in the DIAbetes and LifEstyle Cohort Twente …

CM Gant, SH Binnenmars, E van den Berg, SJL Bakker… - Nutrients, 2017 - mdpi.com
Cardiovascular risk management is an integral part of treatment in Type 2 Diabetes Mellitus
(T2DM), and requires pharmacological as well as nutritional management. We hypothesize …

Update on chronic kidney disease mineral and bone disorder in cardiovascular disease

J Lunyera, JJ Scialla - Seminars in nephrology, 2018 - Elsevier
Chronic kidney disease mineral and bone disorder (MBD) encompasses changes in mineral
ion and vitamin D metabolism that are widespread in the setting of chronic kidney disease …

Phosphorus may induce phenotypic transdifferentiation of vascular smooth muscle cells through the reduction of microRNA-145

S Fernández-Villabrille, B Martín-Carro… - Nutrients, 2023 - mdpi.com
Phosphorus is a vital element for life found in most foods as a natural component, but it is
also one of the most used preservatives added during food processing. High serum …