SUMMARY ATP-binding cassette (ABC) systems are universally distributed among living
organisms and function in many different aspects of bacterial physiology. ABC transporters …

▪ Abstract Rhamnogalacturonan II (RG-II) is a structurally complex pectic polysaccharide that
was first identified in 1978 as a quantitatively minor component of suspension-cultured …

Sialic acids are structurally unique nine-carbon keto sugars occupying the interface between
the host and commensal or pathogenic microorganisms. An important function of host sialic …

The HAD (haloacid dehalogenase) superfamily includes phosphoesterases, ATPases,
phosphonatases, dehalogenases, and sugar phosphomutases acting on a remarkably …

Haloacid dehalogenase (HAD)-like hydrolases are a vast superfamily of largely
uncharacterized enzymes, with a few members shown to possess phosphatase, β …

It is proposed that enzymic phosphoryl-transfer reactions occur by concerted, step-wise,
associative (phosphorane-intermediate) or dissociative (metaphosphate-intermediate) …

The cell envelope of Gram-negative bacteria consists of two distinct membranes, the inner
(IM) and the outer membrane (OM) separated by the periplasm. The OM contains in the …

Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), evades the
antimicrobial defenses of the host and survives within the infected individual through a …

Human PHOSPHO1 is a phosphatase enzyme for which expression is upregulated in
mineralizing cells. This enzyme has been implicated in the generation of Pi for matrix …

The haloacid dehalogenase (HAD)-like enzymes comprise a large superfamily of
phosphohydrolases present in all organisms. The Saccharomyces cerevisiae genome …