[HTML][HTML] Recent developments in lactose blend formulations for carrier-based dry powder inhalation

GA Hebbink, M Jaspers, HJW Peters… - Advanced Drug Delivery …, 2022 - Elsevier
Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

[HTML][HTML] Biopolymeric Inhalable Dry Powders for Pulmonary Drug Delivery

SE Maloney Norcross, LPK Levin, AJ Hickey, DB Hill - Pharmaceuticals, 2024 - mdpi.com
Natural and synthetic biopolymers are gaining popularity in the development of inhaled drug
formulations. Their highly tunable properties and ability to sustain drug release allow for the …

Aspherical, Nano-Structured Drug Delivery System with Tunable Release and Clearance for Pulmonary Applications

T Pioch, T Fischer, M Schneider - Pharmaceutics, 2024 - mdpi.com
Addressing the challenge of efficient drug delivery to the lungs, a nano-structured,
microparticulate carrier system with defined and customizable dimensions has been …

siRNA delivery to macrophages using aspherical, nanostructured microparticles as delivery system for pulmonary administration

T Fischer, T Tschernig, F Drews, K Brix, C Meier… - European Journal of …, 2021 - Elsevier
The delivery of oligonucleotides such as siRNA to the lung is a major challenge, as this
group of drugs has difficulties to overcome biological barriers due to its polyanionic …