Exosomes from the tumor microenvironment as reciprocal regulators that enhance prostate cancer progression

CM Liu, CL Hsieh, CN Shen, CC Lin… - … Journal of Urology, 2016 - Wiley Online Library
Distant organ metastasis of prostate cancer is a puzzle, and various theories have
successively arisen to explain the mechanism of lethal cancer progression. While perhaps …

p0071/PKP4, a multifunctional protein coordinating cell adhesion with cytoskeletal organization

R Keil, J Schulz, M Hatzfeld - Biological chemistry, 2013 - degruyter.com
P0071 is a member of a subfamily of armadillo proteins that also comprises p120-catenin
(p120ctn), δ-catenin/NPRAP, ARVCF and the more distantly related plakophilins 1–3. These …

Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation

C Boykin, G Zhang, YH Chen, RW Zhang… - British journal of …, 2011 - nature.com
Background: Cucurbitacin (Cuc) and triterpene-derived natural products exhibit anti-cancer
potential in addition to their conspicuous anti-bacterial and anti-inflammatory activity …

Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34

KM Williams, S Qie, JH Atkison… - Nature …, 2019 - nature.com
Ubiquitin (Ub) signaling requires the sequential interactions and activities of three enzymes,
E1, E2, and E3. Cdc34 is an E2 that plays a key role in regulating cell cycle progression and …

Differential microRNA-34a expression and tumor suppressor function in retinoblastoma cells

CL Dalgard, M Gonzalez, JE deNiro… - … & visual science, 2009 - iovs.arvojournals.org
purpose. The role of miR-34a, a p53-regulated microRNA, in retinoblastoma (RB) was
investigated. methods. The expression of miR-34 family members in RB cells was …

Detection of CTC clusters and a dedifferentiated RNA‐expression survival signature in prostate cancer

M Kozminsky, S Fouladdel, JS Chung… - Advanced …, 2019 - Wiley Online Library
Rates of progression and treatment response in advanced prostate cancer are highly
variable, necessitating non‐invasive methods to assess the molecular characteristics of …

[HTML][HTML] Relationship between apical junction proteins, gene expression and cancer

L González-Mariscal, J Miranda… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The apical junctional complex (AJC) is a cell-cell adhesion system present at the upper
portion of the lateral membrane of epithelial cells integrated by the tight junction (TJ) and the …

[HTML][HTML] δ-Catenin promotes E-cadherin processing and activates β-catenin-mediated signaling: implications on human prostate cancer progression

H Kim, Y He, I Yang, Y Zeng, Y Kim, YW Seo… - … et Biophysica Acta (BBA …, 2012 - Elsevier
δ-Catenin binds the juxtamembrane domain of E-cadherin and is known to be
overexpressed in some human tumors. However, the functions of δ-catenin in epithelial cells …

Replication study supports CTNND2 as a susceptibility gene for high myopia

B Lu, D Jiang, P Wang, Y Gao, W Sun… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: The CTNND2 gene is located in the linkage interval of high myopia locus MYP16
and two single-nucleotide polymorphisms (SNPs; rs6885224 and rs12716080) in CTNND2 …

δ-Catenin Participates in EGF/AKT/p21Waf Signaling and Induces Prostate Cancer Cell Proliferation and Invasion

Y Shen, HJ Lee, R Zhou, H Kim, G Chen… - International Journal of …, 2021 - mdpi.com
Prostate cancer (PCa) is the second most leading cause of death in males. Our previous
studies have demonstrated that δ-catenin plays an important role in prostate cancer …