Recent applications of fluorescence recovery after photobleaching (FRAP) to membrane bio-macromolecules

G Rayan, JE Guet, N Taulier, F Pincet, W Urbach - Sensors, 2010 - mdpi.com
This review examines some recent applications of fluorescence recovery after
photobleaching (FRAP) to biopolymers, while mainly focusing on membrane protein studies …

Multi-protein assemblies underlie the mesoscale organization of the plasma membrane

SK Saka, A Honigmann, C Eggeling, SW Hell… - Nature …, 2014 - nature.com
Most proteins have uneven distributions in the plasma membrane. Broadly speaking, this
may be caused by mechanisms specific to each protein, or may be a consequence of a …

Proteolipidic composition of exosomes changes during reticulocyte maturation

K Carayon, K Chaoui, E Ronzier, I Lazar… - Journal of Biological …, 2011 - ASBMB
During the orchestrated process leading to mature erythrocytes, reticulocytes must
synthesize large amounts of hemoglobin, while eliminating numerous cellular components …

Insights into cellular signaling from membrane dynamics

P Sarkar, A Chattopadhyay - Archives of Biochemistry and Biophysics, 2021 - Elsevier
Biological membranes allow morphological compartmentalization of cells and represent
complex micro-heterogeneous fluids exhibiting a range of dynamics. The plasma membrane …

EGFR inhibition by curcumin in cancer cells: a dual mode of action

M Starok, P Preira, M Vayssade, K Haupt… - …, 2015 - ACS Publications
Epidermal Growth Factor Receptor (EGFR) is an important target of anticancer therapy.
Nowadays, the search for new molecules inhibiting this receptor is turning toward natural …

Spot variation fluorescence correlation spectroscopy allows for superresolution chronoscopy of confinement times in membranes

V Ruprecht, S Wieser, D Marguet, GJ Schütz - Biophysical journal, 2011 - cell.com
Resolving the dynamical interplay of proteins and lipids in the live-cell plasma membrane
represents a central goal in current cell biology. Superresolution concepts have introduced a …

Intratumoral nanofluidic system enhanced tumor biodistribution of PD‐L1 antibody in triple‐negative breast cancer

HC Liu, S Capuani, AA Badachhape… - Bioengineering & …, 2023 - Wiley Online Library
Immune checkpoint inhibitors (ICI), pembrolizumab and atezolizumab, were recently
approved for treatment‐refractory triple‐negative breast cancer (TNBC), where those with …

Role of actin cytoskeleton in dynamics and function of the serotonin1A receptor

S Shrivastava, P Sarkar, P Preira, L Salomé… - Biophysical journal, 2020 - cell.com
G protein-coupled receptors (GPCRs) are important membrane proteins in higher
eukaryotes that carry out a vast array of cellular signaling and act as major drug targets. The …

Agonist-selective dynamic compartmentalization of human Mu opioid receptor as revealed by resolutive FRAP analysis

AN Sauliere-Nzeh, C Millot, M Corbani… - Journal of Biological …, 2010 - ASBMB
Techniques for analyzing the membrane diffusion of molecules are the most promising
methods for investigating the compartmentalization of G-protein-coupled receptors …

To hop or not to hop: exceptions in the FCS diffusion law

A Gupta, IY Phang, T Wohland - Biophysical Journal, 2020 - cell.com
Diffusion obstacles in membranes have not been directly visualized because of fast
membrane dynamics and the occurrence of subresolution molecular complexes. To …