Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium)-induced hepatotoxicity–A review

K Renu, R Chakraborty, H Myakala, R Koti… - Chemosphere, 2021 - Elsevier
Heavy metals pose a serious threat if they go beyond permissible limits in our bodies. Much
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …

[HTML][HTML] Mechanism of chromium-induced toxicity in lungs, liver, and kidney and their ameliorative agents

R Chakraborty, K Renu, MA Eladl, M El-Sherbiny… - Biomedicine & …, 2022 - Elsevier
Abstract Heavy metal Chromium (Cr), can adversely affect humans and their health if
accumulated in organs of the body, such as the lungs, liver, and kidneys. Cr (VI) is highly …

Rosmarinus officinalis essential oil modulates renal toxicity and oxidative stress induced by potassium dichromate in rats

FM El-Demerdash, RA El-Sayed… - Journal of Trace Elements …, 2021 - Elsevier
BACKGROUND Chromium hexavalent (CrVI) is known as a toxic contaminant that induced
oxidative stress and nephrotoxicity in humans and animals. Rosmarinus officinalis is a …

Oxidative stress and toxicity produced by arsenic and chromium in broiler chicks and application of vitamin E and bentonite as ameliorating agents

J Mashkoor, FA Al-Saeed, Z Guangbin… - Frontiers in Veterinary …, 2023 - frontiersin.org
The present study investigated the adverse effects of arsenic and chromium in broilers and
ascertained the role of vitamin E and bentonite in alleviating their harmful effects. For this …

Recent advances in the mechanism of detoxification of genotoxic and cytotoxic Cr (VI) by microbes

PA Wani, JA Wani, S Wahid - Journal of environmental chemical …, 2018 - Elsevier
Chromium has different oxidation states which ranges between− 2 to+ 6. Among all these
oxidation states, Cr (VI) and Cr (III) are stable but vary in biological, geochemical and …

[HTML][HTML] Cr (VI) induces abnormalities in glucose and lipid metabolism through ROS/Nrf2 signaling

X Li, S He, J Zhou, X Yu, L Li, Y Liu, W Li - … and Environmental Safety, 2021 - Elsevier
The hexavalent form of chromium, Cr (VI), has been associated with various diseases in
humans. In this study, we examined the mechanisms underlying the effect of Cr (VI) on …

Ellagic acid ameliorates hexavalent chromium-induced renal toxicity by attenuating oxidative stress, suppressing TNF-α and protecting mitochondria

MY Cuevas-Magaña, CC Vega-García… - Toxicology and applied …, 2022 - Elsevier
Nephrotoxicity is an important adverse effect of oxidative stress induced by hexavalent
chromium [Cr (VI)]. The effect of ellagic acid, a dietary polyphenolic compound with potent …

Luteolin mitigates potassium dichromate‐induced nephrotoxicity, cardiotoxicity and genotoxicity through modulation of Kim‐1/Nrf2 signaling pathways

OV Awoyomi, YD Adeoye, AA Oyagbemi… - Environmental …, 2021 - Wiley Online Library
Environmental and occupational exposure to chromium compounds has become potential
aetiologic agent for kidney disease with excessive generation of free radicals, apoptosis …

[PDF][PDF] The therapeutic role of chitosan‐saponin‐bentonite nanocomposite on acute kidney injury induced by chromium in male Wistar rats

AA Baiomy, MA Bahaaeldine… - … Research in Applied …, 2023 - biointerfaceresearch.com
Among the toxic metals, naturally occurring heavy metal chromium (Cr) frequently enters the
environment through effluents from different industries. We aimed to assess the protective …

Mitochondrial biogenesis in response to chromium (VI) toxicity in human liver cells

X Zhong, RCS Sá, C Zhong - International journal of molecular sciences, 2017 - mdpi.com
Hexavalent chromium (Cr (VI)) is a ubiquitous environmental pollutant, which poses a threat
to human public health. Recent studies have shown that mitochondrial biogenesis can be …