[HTML][HTML] Neurodevelopmental disorders commonly presenting with sleep disturbances

AR Shelton, B Malow - Neurotherapeutics, 2021 - Elsevier
There are multiple disorders of neurodevelopment that present with co-occurring sleep
disturbances. Many of these neurodevelopmental disorders (NDD) include sleep …

A narrative review of the mechanisms and consequences of intermittent hypoxia and the role of advanced analytic techniques in pediatric autonomic disorders

JM Ramirez, MS Carroll, N Burgraff, CM Rand… - Clinical Autonomic …, 2023 - Springer
Disorders of autonomic functions are typically characterized by disturbances in multiple
organ systems. These disturbances are often comorbidities of common and rare diseases …

Sleep Disturbances as a Manifestation of Neurodevelopmental Disorders

KM Cuthrell, N Tzenios - International Neuropsychiatric Disease …, 2023 - go7publish.com
Sleep disturbances are complex elements of many neurodevelopmental disorders, such as
autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), intellectual …

The pathophysiology of rett syndrome with a focus on breathing dysfunctions

JM Ramirez, M Karlen-Amarante, JDJ Wang… - …, 2020 - journals.physiology.org
Rett syndrome (RTT), an X-chromosome-linked neurological disorder, is characterized by
serious pathophysiology, including breathing and feeding dysfunctions, and alteration of …

Molecular organization and patterning of the medulla oblongata in health and disease

D Diek, MP Smidt, S Mesman - International Journal of Molecular …, 2022 - mdpi.com
The medulla oblongata, located in the hindbrain between the pons and the spinal cord, is an
important relay center for critical sensory, proprioceptive, and motoric information. It is an …

Evaluating sleep disturbances in children with rare genetic neurodevelopmental syndromes

OJ Veatch, BA Malow, HS Lee, A Knight, JO Barrish… - Pediatric …, 2021 - Elsevier
Background Adequate sleep is important for proper neurodevelopment and positive health
outcomes. Sleep disturbances are more prevalent in children with genetically determined …

Dendrimer nanotherapy targeting of glial dysfunction improves inflammation and neurobehavioral phenotype in adult female Mecp2‐heterozygous mouse model of …

ES Khoury, RV Patel, C O'Ferrall… - Journal of …, 2024 - Wiley Online Library
Rett syndrome is an X‐linked neurodevelopmental disorder caused by mutation of Mecp2
gene and primarily affects females. Glial cell dysfunction has been implicated in in Rett …

Breathing disturbances in Rett syndrome

JM Ramirez, M Karlen-Amarante, A Huff… - Handbook of clinical …, 2022 - Elsevier
Rett Syndrome is an X-linked neurological disorder characterized by behavioral and
neurological regression, seizures, motor deficits, and dysautonomia. A particularly …

Breathing abnormalities during sleep and wakefulness in Rett syndrome: clinical relevance and paradoxical relationship with circulating pro-oxidant markers

S Leoncini, C Signorini, L Boasiako… - Frontiers in …, 2022 - frontiersin.org
Background Breathing abnormalities are common in Rett syndrome (RTT), a pervasive
neurodevelopmental disorder almost exclusively affecting females. RTT is linked to …

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

G Matteoli, S Alvente, S Bastianini… - Journal of Sleep …, 2024 - Wiley Online Library
CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5
gene. Central apneas during wakefulness have been reported in patients with CDKL5 …