Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …

The naturally occurring mammalian endocannabinoids possess biological attributes that
extend beyond interaction with cannabinoid receptors. These extended biological properties …

Lipids in the nervous system accomplish a great number of key functions, from
synaptogenesis to impulse conduction, and more. Most of the lipids of the nervous system …

Pharmacologic augmentation of endogenous cannabinoid (eCB) signaling is an emerging
therapeutic approach for the treatment of a broad range of pathophysiological conditions …

It was suggested that endocannabinoids are metabolized by cyclooxygenase (COX)-2 in the
spinal cord of rats with kaolin/λ-carrageenan-induced knee inflammation, and that this …

Background Isoprostanes and prostaglandins are biomarkers for oxidative stress and
inflammation. Their role in Alzheimer's disease (AD) pathophysiology is yet unknown. In the …

Prostamide (prostaglandin ethanolamide) research emerged from two distinct lines of
research: 1) the unique pharmacology of the antiglaucoma drug bimatoprost and 2) the …

The milk fat globule membrane (MFGM) has received great attention due to health-beneficial
properties, highlighting the potential to use MFGM isolates in manufacturing nutraceutical …

Previously, we have demonstrated that prostamide/PGF synthase, which catalyzes the
reduction of prostaglandin (PG) H 2 to PGF 2α, is constitutively expressed in myelin sheaths …

Abstract Background and purpose 4′-O-methylhonokiol (MH) is a natural product showing
anti-inflammatory, anti-osteoclastogenic, and neuroprotective effects. MH was reported to …