Preeclampsia: pathophysiology, challenges, and perspectives

S Rana, E Lemoine, JP Granger… - Circulation …, 2019 - Am Heart Assoc
Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Aspirin use to prevent preeclampsia and related morbidity and mortality: updated evidence report and systematic review for the US Preventive Services Task Force

JT Henderson, KK Vesco, CA Senger, RG Thomas… - Jama, 2021 - jamanetwork.com
Importance Preeclampsia is a hypertensive disorder of pregnancy that poses serious
maternal and infant health risks. Previous systematic reviews have established benefits of …

Pre-eclampsia: pathogenesis, novel diagnostics and therapies

EA Phipps, R Thadhani, T Benzing… - Nature Reviews …, 2019 - nature.com
Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …

[HTML][HTML] Gender differences in cardiovascular disease

Z Gao, Z Chen, A Sun, X Deng - Medicine in Novel Technology and …, 2019 - Elsevier
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. Although
the incidence of CVD in women is usually lower than in men, women have a higher mortality …

Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta …

FJK Toloza, A Derakhshan, T Männistö… - The Lancet Diabetes & …, 2022 - thelancet.com
Background Adequate maternal thyroid function is important for an uncomplicated
pregnancy. Although multiple observational studies have evaluated the association between …

Pre-eclampsia part 1: current understanding of its pathophysiology

T Chaiworapongsa, P Chaemsaithong, L Yeo… - Nature Reviews …, 2014 - nature.com
Pre-eclampsia is characterized by new-onset hypertension and proteinuria at≥ 20 weeks of
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …

The use of sex-specific factors in the assessment of women's cardiovascular risk

A Agarwala, ED Michos, Z Samad, CM Ballantyne… - Circulation, 2020 - Am Heart Assoc
Cardiovascular disease (CVD) is the leading cause of death among women in the United
States. As compared with men, women are less likely to be diagnosed appropriately, receive …

The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

Sex differences in cardiovascular risk factors and disease prevention

Y Appelman, BB van Rijn, ME Ten Haaf, E Boersma… - Atherosclerosis, 2015 - Elsevier
Cardiovascular disease (CVD) has been seen as a men's disease for decades, however it is
more common in women than in men. It is generally assumed in medicine that the effects of …

Incidence of preeclampsia: risk factors and outcomes associated with early-versus late-onset disease

S Lisonkova, KS Joseph - American journal of obstetrics and gynecology, 2013 - Elsevier
Objective The population-based incidence of early-onset (< 34 weeks) and late-onset
preeclampsia (≥ 34 weeks) has not been adequately studied. We examined the gestational …