Polygenic risk scores for cardiovascular disease: a scientific statement from the American Heart Association

JW O'Sullivan, S Raghavan, C Marquez-Luna… - Circulation, 2022 - Am Heart Assoc
Cardiovascular disease is the leading contributor to years lost due to disability or premature
death among adults. Current efforts focus on risk prediction and risk factor mitigation ‚which …

Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review

CLA Navarro, JAA Damen, T Takada, SWJ Nijman… - bmj, 2021 - bmj.com
Objective To assess the methodological quality of studies on prediction models developed
using machine learning techniques across all medical specialties. Design Systematic …

[HTML][HTML] Bias in artificial intelligence algorithms and recommendations for mitigation

LH Nazer, R Zatarah, S Waldrip, JXC Ke… - PLOS Digital …, 2023 - journals.plos.org
The adoption of artificial intelligence (AI) algorithms is rapidly increasing in healthcare. Such
algorithms may be shaped by various factors such as social determinants of health that can …

European Society of Cardiology: cardiovascular disease statistics 2019

A Timmis, N Townsend, CP Gale, A Torbica… - European heart …, 2020 - academic.oup.com
Aims The 2019 report from the European Society of Cardiology (ESC) Atlas provides a
contemporary analysis of cardiovascular disease (CVD) statistics across 56 member …

Sit less and move more for cardiovascular health: emerging insights and opportunities

DW Dunstan, S Dogra, SE Carter… - Nature Reviews Cardiology, 2021 - nature.com
Sedentary behaviour—put simply, too much sitting, as a distinct concept from too little
exercise—is a novel determinant of cardiovascular risk. This definition provides a …

Polygenic risk scores: from research tools to clinical instruments

CM Lewis, E Vassos - Genome medicine, 2020 - Springer
Genome-wide association studies have shown unequivocally that common complex
disorders have a polygenic genetic architecture and have enabled researchers to identify …

PROBAST: a tool to assess the risk of bias and applicability of prediction model studies

RF Wolff, KGM Moons, RD Riley, PF Whiting… - Annals of internal …, 2019 - acpjournals.org
Clinical prediction models combine multiple predictors to estimate risk for the presence of a
particular condition (diagnostic models) or the occurrence of a certain event in the future …

Early detection of type 2 diabetes mellitus using machine learning-based prediction models

L Kopitar, P Kocbek, L Cilar, A Sheikh, G Stiglic - Scientific reports, 2020 - nature.com
Most screening tests for T2DM in use today were developed using multivariate regression
methods that are often further simplified to allow transformation into a scoring formula. The …

Logistic regression was as good as machine learning for predicting major chronic diseases

S Nusinovici, YC Tham, MYC Yan, DSW Ting… - Journal of clinical …, 2020 - Elsevier
Objective To evaluate the performance of machine learning (ML) algorithms and to compare
them with logistic regression for the prediction of risk of cardiovascular diseases (CVDs) …

Reporting of artificial intelligence prediction models

GS Collins, KGM Moons - The Lancet, 2019 - thelancet.com
For more on theTRIPOD statement see https://www. tripodstatement. org technology, and
intelligent monitoring. Behind the digital health revolution are also methodological …