NLR receptors in plant immunity: making sense of the alphabet soup

MP Contreras, D Lüdke, H Pai, AA Toghani… - EMBO …, 2023 - embopress.org
Plants coordinately use cell‐surface and intracellular immune receptors to perceive
pathogens and mount an immune response. Intracellular events of pathogen recognition are …

Assembly and architecture of NLR resistosomes and inflammasomes

Z Hu, J Chai - Annual Review of Biophysics, 2023 - annualreviews.org
Nucleotide-binding and leucine-rich repeat (NLR) proteins are critical intracellular immune
receptors in both animals and plants. Perception of pathogen-derived or stress-associated …

Oligomerization of a plant helper NLR requires cell-surface and intracellular immune receptor activation

JM Feehan, J Wang, X Sun, J Choi… - Proceedings of the …, 2023 - National Acad Sciences
Plant disease resistance involves both detection of microbial molecular patterns by cell-
surface pattern recognition receptors and detection of pathogen effectors by intracellular …

Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor

JHR Maidment, M Shimizu, AR Bentham, S Vera… - Elife, 2023 - elifesciences.org
A subset of plant intracellular NLR immune receptors detect effector proteins, secreted by
phytopathogens to promote infection, through unconventional integrated domains which …

[HTML][HTML] Pathways to engineering plant intracellular NLR immune receptors

R Zdrzałek, C Stone, JC De la Concepcion… - Current Opinion in Plant …, 2023 - Elsevier
Factors including climate change and increased global exchange are set to escalate the
prevalence of plant diseases, posing an unprecedented threat to global food security and …

[HTML][HTML] Barley MLA3 recognizes the host-specificity effector Pwl2 from Magnaporthe oryzae

HJ Brabham, D Gómez De La Cruz, V Were… - The Plant …, 2024 - academic.oup.com
Plant nucleotide-binding leucine-rich repeat (NLRs) immune receptors directly or indirectly
recognize pathogen-secreted effector molecules to initiate plant defense. Recognition of …

Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling

J Chen, X Zhang, JP Rathjen… - Essays in biochemistry, 2022 - portlandpress.com
Plants deploy extracellular and intracellular immune receptors to sense and restrict
pathogen attacks. Rapidly evolving pathogen effectors play crucial roles in suppressing …

Show me your ID: NLR immune receptors with integrated domains in plants

C Marchal, VA Michalopoulou, Z Zou… - Essays in …, 2022 - portlandpress.com
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are intracellular plant immune
receptors that recognize pathogen effectors secreted into the plant cell. Canonical NLRs …

Allelic compatibility in plant immune receptors facilitates engineering of new effector recognition specificities

AR Bentham, JC De la Concepcion… - The Plant …, 2023 - academic.oup.com
Engineering the plant immune system offers genetic solutions to mitigate crop diseases
caused by diverse agriculturally significant pathogens and pests. Modification of intracellular …

Resistosomes at the interface of pathogens and plants

A Förderer, D Yu, E Li, J Chai - Current Opinion in Plant Biology, 2022 - Elsevier
Nucleotide-binding and leucine-rich repeat (NLR) proteins are a large family of intracellular
immune receptors that detect specific pathogen effector proteins secreted into plant cells …