Mitochondrial DNA release contributes to intestinal ischemia/reperfusion injury

S Liao, J Luo, T Kadier, K Ding, R Chen… - Frontiers in …, 2022 - frontiersin.org
Mitochondria release many damage-associated molecular patterns (DAMPs) when cells are
damaged or stressed, with mitochondrial DNA (mtDNA) being. MtDNA activates innate …

Role of innate immunity and oxidative stress in the development of type 1 diabetes mellitus. Peroxiredoxin 6 as a new anti-diabetic agent

EG Novoselova, OV Glushkova, MO Khrenov… - Biochemistry …, 2021 - Springer
The review discusses information on the development of type 1 diabetes mellitus (T1D) as a
systemic autoimmune and inflammatory disease. Focus of the review is on the role of innate …

Prospects of intraoperative multimodal OCT application in patients with acute mesenteric ischemia

E Kiseleva, M Ryabkov, M Baleev, E Bederina… - Diagnostics, 2021 - mdpi.com
Introduction: Despite the introduction of increasingly multifaceted diagnostic techniques and
the general advances in emergency abdominal and vascular surgery, the outcome of …

Protective effect of peroxiredoxin 6 against toxic effects of glucose and cytokines in pancreatic RIN-m5F β-cells

EG Novoselova, OV Glushkova, SB Parfenuyk… - Biochemistry …, 2019 - Springer
Taking into account a special role of pancreatic β-cells in the development of diabetes
mellitus, the effects of peroxiredoxin 6 (Prx6) on the viability and functional activity of rat …

Peroxiredoxin 6 applied after exposure attenuates damaging effects of X-ray radiation in 3T3 mouse fibroblasts

EG Novoselova, MG Sharapov, SM Lunin… - Antioxidants, 2021 - mdpi.com
Although many different classes of antioxidants have been evaluated as radioprotectors,
none of them are in widespread clinical use because of their low efficiency. The goal of our …

Endogenous humoral determinants of vascular endothelial dysfunction as triggers of acute poisoning complications

JJ Ivnitsky, TV Schäfer, VL Rejniuk… - Journal of Applied …, 2023 - Wiley Online Library
The vascular endothelium is not only the semipermeable membrane that separates tissue
from blood but also an organ that regulates inflammation, vascular tone, blood clotting …

The curative effect of cannabinoid 2 receptor agonist on functional failure and disruptive inflammation caused by intestinal ischemia and reperfusion

S Bayram, A Parlar, SO Arslan - Fundamental & Clinical …, 2020 - Wiley Online Library
Ischemia and reperfusion of intestinal tissue (intestinal I/R) induce disruption of ileal
contractility and chain responses of inflammatory. The aim of this study was to reveal …

Regulation of the Nrf2/HO-1 axis by mesenchymal stem cells-derived extracellular vesicles: implications for disease treatment

H Su, Z Wang, L Zhou, D Liu, N Zhang - Frontiers in Cell and …, 2024 - frontiersin.org
This comprehensive review inspects the therapeutic potential of mesenchymal stem cell-
derived extracellular vesicles (MSC-EVs) across multiple organ systems. Examining their …

Changes in the sublingual microcirculation following aortic surgery under balanced or total intravenous anaesthesia: a prospective observational study

S Loggi, N Mininno, E Damiani, B Marini, E Adrario… - BMC …, 2019 - Springer
Background In vascular surgery with aortic cross-clamping, ischemia/reperfusion injury
induces systemic haemodynamic and microcirculatory disturbances. Different anaesthetic …

Trans-serosal multimodal optical coherence tomography for visualization of microstructure and blood circulation of the small intestine wall

MG Ryabkov, EB Kiseleva, MS Baleev… - Современные …, 2020 - cyberleninka.ru
Materials and Methods. In experiments on Wistar rats (n= 22), we examined the small
intestine wall in vivo using MM OCT; the access to the intestine was reached through …