The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

Bacterial superinfections among persons with coronavirus disease 2019: a comprehensive review of data from postmortem studies

CJ Clancy, IS Schwartz, B Kula… - Open Forum Infectious …, 2021 - academic.oup.com
Background Limited clinical data suggest a~ 16% prevalence of bacterial superinfections
among critically ill patients with coronavirus disease 2019 (COVID-19). Methods We …

Invasive mould disease in fatal COVID-19: a systematic review of autopsies

BE Kula, CJ Clancy, MH Nguyen, IS Schwartz - The Lancet Microbe, 2021 - thelancet.com
Invasive mould disease (IMD) might affect up to a third of critically ill patients with COVID-19.
COVID-19-associated pulmonary aspergillosis (CAPA) is typically diagnosed on the basis of …

Identifying COVID-19 by using spectral analysis of cough recordings: a distinctive classification study

N Melek Manshouri - Cognitive neurodynamics, 2022 - Springer
Sound signals from the respiratory system are largely taken as tokens of human health.
Early diagnosis of respiratory tract diseases is of great importance because, if delayed, it …

Platelet-leukocyte crosstalk in COVID-19: How might the reciprocal links between thrombotic events and inflammatory state affect treatment strategies and disease …

M Ghasemzadeh, J Ahmadi, E Hosseini - Thrombosis research, 2022 - Elsevier
Platelet-leukocyte crosstalk is commonly manifested by reciprocal links between thrombosis
and inflammation. Platelet thrombus acts as a reactive matrix that recruits leukocytes to the …

Cause of death based on systematic post‐mortem studies in patients with positive SARS‐CoV‐2 tissue PCR during the COVID‐19 pandemic

ES Romanova, VV Vasilyev, G Startseva… - Journal of internal …, 2021 - Wiley Online Library
Importance Assessment of the causative association between the COVID‐19 and cause of
death has been hampered by limited availability of systematically performed autopsies. We …

Implications of microscale lung damage for COVID-19 pulmonary ventilation dynamics: a narrative review

E Dimbath, V Maddipati, J Stahl, K Sewell, Z Domire… - Life Sciences, 2021 - Elsevier
The COVID-19 pandemic surges on as vast research is produced to study the novel SARS-
CoV-2 virus and the disease state it induces. Still, little is known about the impact of COVID …

Cellular metabolic basis of altered immunity in the lungs of patients with COVID-19

S Li, F Zhao, J Ye, K Li, Q Wang, Z Du, Q Yue… - Medical microbiology …, 2022 - Springer
Metabolic pathways drive cellular behavior. Severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection causes lung tissue damage directly by targeting cells or indirectly …

[HTML][HTML] Acute lung injury—from cannabis to COVID

MB Beasley - Modern pathology, 2022 - Elsevier
Recent world events have refocused attention on the pathology associated with clinical
acute respiratory distress syndrome (ARDS). The vast majority of cases of clinical ARDS will …

Antemortem vs postmortem histopathologic and ultrastructural findings in paired transbronchial biopsy specimens and lung autopsy samples from three patients with …

D Gagiannis, VG Umathum, W Bloch… - American Journal of …, 2022 - academic.oup.com
Objectives Respiratory failure is the major cause of death in coronavirus disease 2019
(COVID-19). Autopsy-based reports describe diffuse alveolar damage (DAD), organizing …