Sexually transmitted infections: challenges ahead

M Unemo, CS Bradshaw, JS Hocking… - The Lancet infectious …, 2017 - thelancet.com
WHO estimated that nearly 1 million people become infected every day with any of four
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …

[HTML][HTML] Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

VA Fonner, SL Dalglish, CE Kennedy, R Baggaley… - Aids, 2016 - journals.lww.com
Objective: Preexposure prophylaxis (PrEP) offers a promising new approach to HIV
prevention. This systematic review and meta-analysis evaluated the evidence for use of oral …

Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a …

KH Mayer, JM Molina, MA Thompson, PL Anderson… - The Lancet, 2020 - thelancet.com
Background Tenofovir alafenamide shows high antiviral efficacy and improved renal and
bone safety compared with tenofovir disoproxil fumarate when used for HIV treatment. Here …

[HTML][HTML] Artificial intelligence and the implementation challenge

J Shaw, F Rudzicz, T Jamieson, A Goldfarb - Journal of medical Internet …, 2019 - jmir.org
Background Applications of artificial intelligence (AI) in health care have garnered much
attention in recent years, but the implementation issues posed by AI have not been …

Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study

JM Molina, I Charreau, B Spire, L Cotte, J Chas… - The lancet HIV, 2017 - thelancet.com
Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We
implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour …

Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2016 recommendations of the International Antiviral Society–USA panel

HF Günthard, MS Saag, CA Benson, C Del Rio, JJ Eron… - Jama, 2016 - jamanetwork.com
Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …

Effects of pre-exposure prophylaxis for the prevention of human immunodeficiency virus infection on sexual risk behavior in men who have sex with men: a systematic …

MW Traeger, SE Schroeder, EJ Wright… - Clinical Infectious …, 2018 - academic.oup.com
Background Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is
effective in reducing HIV risk in men who have sex with men (MSM). However, concerns …

[HTML][HTML] The prevalence of pre-exposure prophylaxis use and the pre-exposure prophylaxis–to-need ratio in the fourth quarter of 2017, United States

AJ Siegler, F Mouhanna, RM Giler, K Weiss… - Annals of …, 2018 - Elsevier
Purpose The number of individuals who have started a regimen for HIV pre-exposure
prophylaxis (PrEP) in the United States is not well characterized but has been on the rise …

An update on the global epidemiology of syphilis

N Kojima, JD Klausner - Current epidemiology reports, 2018 - Springer
Abstract Purpose of Review Syphilis continues to cause morbidity and mortality worldwide.
While syphilis infection is easily identifiable and treatable, rates of syphilis infection continue …

PrEP stigma: implicit and explicit drivers of disparity

SA Golub - Current HIV/AIDS Reports, 2018 - Springer
Abstract Purpose of Review Despite its promise as an HIV prevention strategy, PrEP uptake
remains slow, especially among highest priority populations. One factor that may be …