The estrogen receptor is a vital receptor for therapeutic targets in estrogen receptor-positive
breast cancer. The main strategy for the treatment of estrogen receptor-positive breast …

Nuclear factor-kappaB (NF-ĸB) plays a crucial role in both innate and adaptive immune
systems, significantly influencing various physiological processes such as cell proliferation …

Breast cancer is the most common malignant tumor in females worldwide. Chemotherapy is
the standard breast cancer treatment; however, chemoresistance is often seen in patients …

Chemotherapy is an important tool for the management of solid tumors including breast
cancers (BC). Its neo-adjuvant and adjuvant use is important for shrinking tumor size and …

Recent years have seen an outstanding growth in the understanding of connections
between diet-induced obesity, dysbiosis and alterations in the tumor microenvironment. Now …

The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …

Natural products are being targeted as alternative anticancer agents due to their non-toxic
and safe nature. The present study was conducted to explore the in vitro anticancer potential …

Breast cancer is the most frequent female malignant tumor, and the leading cause of cancer
death in women worldwide. The most common subtype of breast cancer is hormone receptor …

Background Recently, we reported that tamoxifen-resistant (TAM-R) breast cancer cells are
cross-resistant to irradiation. Here, we investigated the mechanisms associated with …

The development of tumor therapeutic resistance is one of the important reasons for the
failure of antitumor therapy. Starting with multiple targets and multiple signaling pathways is …