Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

Epilepsy is a chronic brain disease that affects approximately 65 million people worldwide.
However, despite the continuous development of antiepileptic drugs, over 30% patients with …

The aim of this work is to provide a comprehensive and unbiased understanding at the
molecular correlates of peripheral nerve injury. In this study, we screened the differentially …

Galanin is a highly inducible neuropeptide, showing distinct up-regulation after pathological
disturbance within the nervous system. Significant increase in galanin expression is …

Galanin is a neuropeptide expressed in a small percentage of sensory neurons of the dorsal
root ganglia and the superficial lamina of the dorsal horn of the spinal cord. In this work, we …

The neuropeptide galanin is expressed in the dorsal root ganglia (DRG) and spinal cord and
is thought to be involved in the modulation of pain processing. However, its mechanisms of …

Interleukin-6 (IL-6) is a neuropoietic cytokine which is dramatically upregulated following
peripheral nerve injury at the site of injury, in the dorsal root ganglion (DRG) and in the …

A large number of neuroanatomical, neurophysiologic, and neurochemical mechanisms are
thought to contribute to the development and maintenance of neuropathic pain. However …

It is believed that neuropathic pain results from aberrant neuronal discharges although some
evidence suggests that the activation of glia cells contributes to pain after an injury to the …