Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Lipid-based carriers represent the most widely used alternative to viral vectors for gene
expression and gene silencing purposes. This class of non-viral vectors is particularly …

The two-volume Encyclopedia of Supramolecular Chemistry offers authoritative, centralized
information on a rapidly expanding interdisciplinary field. User-friendly and high-quality …

This review makes an attempt to combine the insights gained into the biochemistry and
physiology of bile acids with the elegant supramolecular systems designed from them. Bile …

A series of hydrazones synthesized from various cholesterol derivatives were evaluated for
their in vitro antimicrobial properties against human pathogens. The activity was highly …

The structure of cationic lipids is a major factor for their transfection activity. A cationic lipid
generally contains four functional domains: a hydrophilic headgroup, a linker, a backbone …

Poly (2-(dimethylamino) ethyl methacrylate)(PDMAEMA) is a water-soluble cationic polymer,
which is able to bind to DNA by electrostatic interactions. At a polymer/plasmid ratio above 2 …

The prevalence of drug-resistant bacteria drives the quest for new antimicrobials, including
those that are not expected to readily engender resistance. One option is to mimic Nature's …

Cationic steroid antibiotics have been developed that display broad-spectrum antibacterial
activity. These compounds are comprised of steroids appended with amine groups arranged …

This feature article describes the recent developments in the design of cationic lipids and
their applications in gene delivery. Various structure–activity investigations explaining the …