Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease
EA Homan, A Gilani, A Rubio-Navarro, MA Johnson… - eLife, 2025 - elifesciences.org
Together with obesity and type 2 diabetes, metabolic dysfunction-associated steatotic liver
disease (MASLD) is a growing global epidemic. Activation of the complement system and …
disease (MASLD) is a growing global epidemic. Activation of the complement system and …
C3aR1 on β cells enhances β cell function and survival
R Lima, A Li, A Gilani, J Lo - bioRxiv, 2024 - biorxiv.org
Pancreatic β cell dysfunction is critical to the development of type 2 diabetes (T2D). We
show that the complement receptor C3aR1 on β cells plays an essential role in maintaining …
show that the complement receptor C3aR1 on β cells plays an essential role in maintaining …