The neuropsychiatry of Parkinson's disease: advances and challenges

D Weintraub, D Aarsland, KR Chaudhuri… - The Lancet …, 2022 - thelancet.com
In people with Parkinson's disease, neuropsychiatric signs and symptoms are common
throughout the disease course. These symptoms can be disabling and as clinically relevant …

[HTML][HTML] The role of dopamine in the brain-lessons learned from Parkinson's disease

D Meder, DM Herz, JB Rowe, S Lehéricy, HR Siebner - Neuroimage, 2019 - Elsevier
Parkinson's disease causes a characteristic combination of motor symptoms due to
progressive neurodegeneration of dopaminergic neurons in the substantia nigra pars …

The neuropsychiatry of Parkinson disease: a perfect storm

D Weintraub, E Mamikonyan - The American Journal of Geriatric Psychiatry, 2019 - Elsevier
Affective disorders, cognitive decline, and psychosis have long been recognized as common
in Parkinson disease (PD), and other psychiatric disorders include impulse control …

Impulse control disorders in Parkinson's disease. A brief and comprehensive review

EM Gatto, V Aldinio - Frontiers in neurology, 2019 - frontiersin.org
Impulse control and related disorders (ICDs-RD) encompasses a heterogeneous group of
disorders that involve pleasurable behaviors performed repetitively, excessively, and …

Impulse control disorder in Parkinson's disease: a meta-analysis of cognitive, affective, and motivational correlates

A Martini, D Dal Lago, NMJ Edelstyn, JA Grange… - Frontiers in …, 2018 - frontiersin.org
Background: In Parkinson's disease (PD), impulse control disorders (ICDs) develop as side-
effect of dopaminergic replacement therapy (DRT). Cognitive, affective, and motivational …

Impulse control disorder in Parkinson's disease is associated with abnormal frontal value signalling

JG Tichelaar, C Sayalı, RC Helmich, R Cools - Brain, 2023 - academic.oup.com
Dopaminergic medication is well established to boost reward-versus punishment-based
learning in Parkinson's disease. However, there is tremendous variability in dopaminergic …

Impulse control disorders in Parkinson's disease: epidemiology, pathogenesis and therapeutic strategies

JF Zhang, XX Wang, Y Feng, R Fekete… - Frontiers in …, 2021 - frontiersin.org
Impulse control disorders (ICDs) in Parkinson's disease (PD) are aberrant behavior such as
pathological gambling, hypersexuality, binge eating, and compulsive buying, which typically …

The role of dopamine pharmacotherapy and addiction-like behaviors in Parkinson's disease

TC Napier, A Kirby, AL Persons - Progress in Neuro-Psychopharmacology …, 2020 - Elsevier
Addictions involve a spectrum of behaviors that encompass features of impulsivity and
compulsivity, herein referred to as impulsive-compulsive spectrum disorders (ICSDs). The …

Role of dopamine and clinical heterogeneity in cognitive dysfunction in Parkinson's disease

R Cools, JG Tichelaar, RCG Helmich, BR Bloem… - Progress in brain …, 2022 - Elsevier
Parkinson's disease (PD) is commonly treated with dopaminergic medication, which
enhances some, while impairing other cognitive functions. It can even contribute to impulse …

Treatment of nonmotor symptoms associated with Parkinson disease

JG Goldman, CM Guerra - Neurologic clinics, 2020 - neurologic.theclinics.com
Parkinson disease (PD) is well recognized as a complex neurodegenerative disorder with a
myriad of motor and nonmotor symptoms. 1, 2 Nonmotor symptoms can predate the classic …