Immunohistochemistry in the Diagnosis and Classification of Breast Tumors

H Sun, Q Ding, AA Sahin - Archives of Pathology & …, 2023 - meridian.allenpress.com
Context.—In the clinical practice of breast pathology, immunohistochemistry (IHC) of
different markers is widely used for the diagnosis and classification of breast lesions …

[HTML][HTML] A Comprehensive Review of TRPS1 as a Diagnostic Immunohistochemical Marker for Primary Breast Carcinoma: Latest Insights and Diagnostic Pitfalls

AC Georgescu, TA Georgescu, SA Duca-Barbu… - Cancers, 2024 - mdpi.com
Abstract Background/Objectives: Immunohistochemical expression of TRPS1
(trichorhinophalangeal syndrome type 1) protein is usually used by pathologists to confirm …

Application of novel transcription factor machine learning model and targeted drug combination therapy strategy in triple negative breast cancer

J Pang, H Li, X Zhang, Z Luo, Y Chen, H Zhao… - International Journal of …, 2023 - mdpi.com
Transcription factors (TFs) have been shown to play a key role in the occurrence and
development of tumors, including triple-negative breast cancer (TNBC), with a worse …

Trichorhinophalangeal syndrome 1 expression in breast and nonbreast metastases from Müllerian, lung, gastrointestinal tract, and pancreatic primary tumors by …

D Donthi, Q Gan, QQ Ding… - Cancer …, 2024 - Wiley Online Library
Abstract Background Trichorhinophalangeal syndrome 1 (TRPS1) expression in primary
breast and other solid tumors has been investigated but its role as a marker in metastatic …

TRPS1 function beyond breast: A retrospective immunohistochemical study on non‐breast cytology specimens

A Ali, S Geetha, D Wu, K Chau, P Karam… - Diagnostic …, 2024 - Wiley Online Library
Introduction Trichorhinophalangeal syndrome type 1 (TRPS1) has emerged as a reliable
immunohistochemistry (IHC) marker for identifying breast origin in metastatic carcinomas …

TRPS1 outperforms GATA3 in pleural effusions with metastatic breast carcinoma versus mesothelioma

F Baban, JW Koepplin, M Ahmad… - Diagnostic …, 2023 - Wiley Online Library
Introduction In evaluating malignant pleural fluid cytology, metastatic adenocarcinomas and
mesotheliomas are often differential diagnoses. GATA binding protein 3 (GATA3) has …

Metastatic breast cancer: cytology diagnosis with implications for treatment

A Hrizat, E Brachtel - Journal of Molecular Pathology, 2022 - mdpi.com
Breast cancer is among the most frequent malignancies in women worldwide. While early
detection and effective treatment provide many women with a cure and prevent their cancer …

TRPS1 is a Highly Sensitive Marker for Breast Cancer: A Tissue Microarray Study Evaluating More Than 19,000 Tumors From 152 Different Tumor Entities

M Lennartz, N Löhr, D Höflmayer, SD Rico… - The American Journal …, 2024 - journals.lww.com
Abstract Trichorhinophalangeal syndrome 1 (TRPS1) is a nuclear protein highly expressed
in breast epithelial cells. TRPS1 immunohistochemistry (IHC) has been suggested as a …

TRPS1, a New Promising Marker for Assessment of Distant Metastatic Breast Cancer

PJ McIntire, LA Duckworth, J Van Arnam… - Advances in …, 2023 - journals.lww.com
This article reviewed the identification of breast cancer in the distant metastatic setting
through traditional immunohistochemical markers, such as mammaglobin and GATA3 …

Utility of Wnt family member 9b (Wnt9b) immunohistochemistry in the cytologic diagnosis of metastatic breast carcinoma

Y Baykara, S Lu, D Yang, Y Wang, E Yakirevich… - Virchows Archiv, 2023 - Springer
Wnt family member 9b (Wnt9b) has been demonstrated as a valuable marker for breast
cancer diagnosis in surgical pathology. In this study, we examined the utility of Wnt9b in …