On the run for hippocampal plasticity

HY Moon, H van Praag - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Accumulating research in rodents and humans indicates that exercise benefits brain function
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …

[HTML][HTML] The pilocarpine model of epilepsy: what have we learned?

FA Scorza, RM Arida… - Anais da Academia …, 2009 - SciELO Brasil
The systemic administration of a potent muscarinic agonist pilocarpine in rats promotes
sequential behavioral and electrographic changes that can be divided into 3 distinct …

Epilepsy, seizures, physical exercise, and sports: A report from the ILAE Task Force on Sports and Epilepsy

G Capovilla, KR Kaufman, E Perucca, SL Moshe… - …, 2016 - Wiley Online Library
People with epilepsy (PWE s) are often advised against participating in sports and exercise,
mostly because of fear, overprotection, and ignorance about the specific benefits and risks …

The effects of hormones and physical exercise on hippocampal structural plasticity

J Triviño-Paredes, AR Patten, J Gil-Mohapel… - Frontiers in …, 2016 - Elsevier
The hippocampus plays an integral role in certain aspects of cognition. Hippocampal
structural plasticity and in particular adult hippocampal neurogenesis can be influenced by …

Physical activity and epilepsy: proven and predicted benefits

RM Arida, EA Cavalheiro, AC Da Silva, FA Scorza - Sports medicine, 2008 - Springer
Epilepsy is a common disease found in 2% of the population, affecting people from all ages.
Unfortunately, persons with epilepsy have previously been discouraged from participation in …

Forced, moderate-intensity treadmill exercise suppresses apoptosis by increasing the level of NGF and stimulating phosphatidylinositol 3-kinase signaling in the …

CH Chae, HT Kim - Neurochemistry international, 2009 - Elsevier
While nerve growth factor (NGF) activates various signaling cascades, the
phosphatidylinositol 3-kinase (PI3-K)/Akt pathway plays a pivotal role in controlling the …

The relationship between physical activity and cognitive function in people with epilepsy: A systematic review

HB Alexander, JB Allendorfer - Epilepsy & Behavior, 2023 - Elsevier
Background This study aimed to systematically review the published literature evaluating the
association between physical activity and cognitive function in people with epilepsy (PWE) …

Epilepsy, physical activity and sports: a narrative review

J Carrizosa-Moog, LD Ladino… - Canadian Journal of …, 2018 - cambridge.org
People with epilepsy (PWE) are less physically active compared with the general
population. Explanations include prejudice, overprotection, unawareness, stigma, fear of …

[HTML][HTML] Experimental and clinical findings from physical exercise as complementary therapy for epilepsy

RM Arida, ACG de Almeida, EA Cavalheiro… - Epilepsy & behavior, 2013 - Elsevier
Complementary therapies for preventing or treating epilepsy have been extensively used.
This review focuses on the positive effects of physical exercise programs observed in clinical …

Hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant effects of running exercise

J Wang, J Tang, X Liang, Y Luo, P Zhu, Y Li… - Translational …, 2021 - nature.com
Running exercise was shown to have a positive effect on depressive-like symptoms in many
studies, but the underlying mechanism of running exercise in the treatment of depression …