Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Mimicking complex biological membranes and their programmable glycan ligands with dendrimersomes and glycodendrimersomes

SE Sherman, Q Xiao, V Percec - Chemical reviews, 2017 - ACS Publications
Synthetic vesicles have been assembled and coassembled from phospholipids, their
modified versions, and other single amphiphiles into liposomes, and from block copolymers …

Protein cages and synthetic polymers: a fruitful symbiosis for drug delivery applications, bionanotechnology and materials science

M Rother, MG Nussbaumer, K Renggli… - Chemical Society …, 2016 - pubs.rsc.org
Protein cages are hollow protein nanoparticles, such as viral capsids, virus-like particles,
ferritin, heat-shock proteins and chaperonins. They have well-defined capsule-like structures …

[HTML][HTML] Self-assembly and modular functionalization of three-dimensional crystals from oppositely charged proteins

V Liljeström, J Mikkilä, MA Kostiainen - Nature Communications, 2014 - nature.com
Multicomponent crystals and nanoparticle superlattices are a powerful approach to integrate
different materials into ordered nanostructures. Well-developed, especially DNA-based …

Cationic polymer brush-modified cellulose nanocrystals for high-affinity virus binding

H Rosilo, JR McKee, E Kontturi, T Koho, VP Hytönen… - Nanoscale, 2014 - pubs.rsc.org
Surfaces capable of high-affinity binding of biomolecules are required in several
biotechnological applications, such as purification, transfection, and sensing. Therein, the …

Electrostatic self-assembly of soft matter nanoparticle cocrystals with tunable lattice parameters

V Liljestrom, J Seitsonen, MA Kostiainen - Acs Nano, 2015 - ACS Publications
Atomic crystal structure affects the electromagnetic and thermal properties of common
matter. Similarly, the nanoscale structure controls the properties of higher length-scale …

Highly ordered protein cage assemblies: A toolkit for new materials

A Korpi, E Anaya‐Plaza, S Välimäki… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Protein capsids are specialized and versatile natural macromolecules with exceptional
properties. Their homogenous, spherical, rod‐like or toroidal geometry, and spatially …

Slow‐release formulation of cowpea mosaic virus for in situ vaccine delivery to treat ovarian cancer

AE Czapar, BDB Tiu, FA Veliz, JK Pokorski… - Advanced …, 2018 - Wiley Online Library
The plant viral nanoparticle cowpea mosaic virus (CPMV) is shown to be an effective
immunotherapy for ovarian cancer when administered as in situ vaccine weekly, directly into …

Hierarchical organization of organic dyes and protein cages into photoactive crystals

J Mikkilä, E Anaya-Plaza, V Liljeström, JR Caston… - ACS …, 2016 - ACS Publications
Phthalocyanines (Pc) are non-natural organic dyes with wide and deep impact in materials
science, based on their intense absorption at the near-infrared (NIR), long-lived …