[HTML][HTML] Electrophilic metabolites targeting the KEAP1/NRF2 partnership

AT Dinkova-Kostova, H Hakomäki… - Current Opinion in …, 2024 - Elsevier
Numerous electrophilic metabolites are formed during cellular activity, particularly under
conditions of oxidative, inflammatory and metabolic stress. Among them are lipid oxidation …

A multilayer hydrogel incorporating urolithin B promotes diabetic wound healing via ROS scavenging and angiogenesis

J Li, Y Shen, X Wang, T Wu, Q Huang, M Shen… - Chemical Engineering …, 2024 - Elsevier
Impaired wound healing is one of the most prevalent complications associated with
diabetes. Reactive oxygen species (ROS) and subsequent endothelial dysfunction are the …

OPA1 Mediated Fatty Acid β‐Oxidation in Hepatocyte: The Novel Insight for Melatonin Attenuated Apoptosis in Concanavalin A Induced Acute Liver Injury

T Chen, R Shuang, T Gao, L Ai, J Diao… - Journal of Pineal …, 2024 - Wiley Online Library
Melatonin (MLT) has been reported to attenuate Concanavalin A (Con A)‐induced acute
liver injury via the inhibition of immune cells. Whereas the response of hepatocyte to Con A …

[HTML][HTML] BACH1 impairs hepatocyte regeneration after hepatectomy with repeated ischemia/reperfusion by reprogramming energy metabolism and exacerbating …

Y Hu, J Li, L Hu, F Liu, R Chen, L Xu, Z Tang… - Biochemical …, 2024 - Elsevier
Abstract BTB and CNC homology 1 (BACH1) regulates biological processes, including
energy metabolism and oxidative stress. Insufficient liver regeneration after hepatectomy …