Uterine luminal epithelium as the transient gateway for embryo implantation

X Ye - Trends in Endocrinology & Metabolism, 2020 - cell.com
The uterine luminal epithelium (LE) is the first maternal contact for an implanting embryo.
Intrauterine fluid resorption, cessation of LE proliferation and apoptosis, and LE structural …

The molecular mechanisms of HLA-G regulatory function on immune cells during early pregnancy

J Mao, Y Feng, X Zhu, F Ma - Biomolecules, 2023 - mdpi.com
Human leukocyte antigen-G (HLA-G) is a non-classical human major histocompatibility
complex (MHC-I) molecule with the membrane-bound and soluble types. HLA-G is primarily …

[HTML][HTML] Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice

S Aikawa, M Matsuo, S Akaeda, Y Sugimoto… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Embryo implantation is crucial for ensuring a successful pregnancy outcome and
subsequent child health. The intrauterine environment during the peri-implantation period …

Effect of NETs/COX-2 pathway on immune microenvironment and metastasis in gastric cancer

A Zhang, X Zou, S Yang, H Yang, Z Ma, J Li - Frontiers in Immunology, 2023 - frontiersin.org
Background Neutrophil extracellular traps (NETs) are crucial in the progression of several
cancers. The formation of NETs is closely related to reactive oxygen species (ROS), and the …

Roles of lipid mediators in early pregnancy events

S Aikawa, Y Hirota - Reproductive Medicine and Biology, 2024 - Wiley Online Library
Background Early pregnancy events, including embryo implantation, are critical for
maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling …

Maternal-fetal toxicity of Strychnos pseudoquina extract treatment during pregnancy

MR Souza, ECB Brito, LS Furtado, VS Barco… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Plants and herbs have been used by women throughout
history for therapeutic purposes. Strychnos pseudoquina, a plant used in the treatment of …

Natural mating differentially triggers expression of glucocorticoid receptor (NR3C1)-related genes in the preovulatory porcine female reproductive tract

M Ruiz-Conca, J Gardela, CA Martínez… - International journal of …, 2020 - mdpi.com
Mating initiates dynamic modifications of gene transcription in the female reproductive tract,
preparing the female for fertilization and pregnancy. Glucocorticoid signaling is essential for …

Signaling pathways mediating bradykinin-induced contraction in murine and human detrusor muscle

K Borsodi, H Balla, PJ Molnár, Á Lénárt… - Frontiers in …, 2022 - frontiersin.org
Bradykinin (BK) has been proposed to modulate urinary bladder functions and implicated in
the pathophysiology of detrusor overactivity. The present study aims to elucidate the …

Embryo–Uterine Cross-Talk: Exploration of the Immunomodulatory Mechanism in Buffalo

LD Huidrom, SN Dhanaji, S Pandey, V Chandra… - Animals, 2022 - mdpi.com
Simple Summary Early embryonic loss is the major cause of repeat breeding in buffalo. For
successful pregnancy outcomes, proper communication between the embryo and maternal …

New insights into the obligatory nature of cyclooxygenase-2 and PGE2 during early chick embryogenesis

U Verma, M Gautam, B Parmar, K Khaire… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Temporal expression patterns and activity of two cyclooxygenase (COX-1 and COX-2)
isoforms were analysed during early chick embryogenesis to evaluate their roles in …