The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Microplastics in the environment produced by decomposition of globally increasing waste
plastics have become a dominant component of both water and air pollution. To examine the …

Cough is the most common reason for patients to visit a primary care physician, yet it
remains an unmet medical need. It can be idiopathic in nature but can also be a …

Each year, the general public and wildland firefighters in the US are exposed to smoke from
wildland fires. As part of an effort to characterize health risks of breathing this smoke, a …

Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …

The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of
channels, is primarily localized to a subpopulation of primary sensory neurons of the …

Over the last few decades, there has been an explosion of scientific publications reporting
the many and varied roles of transient receptor potential (TRP) ion channels in physiological …

TRPV1 and TRPA1 are cation channels that play key roles in inflammatory signaling
pathways. They are co-expressed on airway C-fibers, where they exert synergistic effects on …

Exposure to household air pollution (HAP) from solid fuel combustion affects almost half of
the world population. Adverse respiratory outcomes such as respiratory infections, impaired …