Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …

Resveratrol (3, 4′, 5-trihy-droxystilbene), a natural phytoalexin polyphenol, exhibits anti-
oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well …

In castration-resistant prostate cancer (CRPC), the loss of androgen receptor (AR)
dependence leads to clinically aggressive tumors with few therapeutic options. We used …

Single-cell multi-omics (scMulti-omics) allows the quantification of multiple modalities
simultaneously to capture the intricacy of complex molecular mechanisms and cellular …

MAPK (mitogen-activated protein kinase) signaling pathways regulate a variety of biological
processes through multiple cellular mechanisms. In most of these processes, such as …

Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

Epithelial–mesenchymal transition (EMT) is a process in which epithelial cells acquire
mesenchymal features. In cancer, EMT is associated with tumor initiation, invasion …

Further advances in cell engineering are needed to increase the efficacy of chimeric antigen
receptor (CAR) and other T cell-based therapies,,,–. As T cell differentiation and functional …

Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2
infection, although the mechanism for initiation of a hyper-inflammatory response, and multi …

Gene transcription is the process by which the genetic codes of organisms are read and
interpreted as a set of instructions for cells to divide, differentiate, migrate, and mature. As …