There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

The sequencing of the Strongylocentrotus purpuratus genome provides a unique
opportunity to investigate the function and evolution of neural genes. The neurobiology of …

Ingestion of vertebrate blood is essential for egg maturation and transmission of disease-
causing parasites by female mosquitoes. Prior studies with the yellow fever mosquito, Aedes …

Relaxin-3 (RLX3) is a newly identified member of the relaxin/insulin peptide family that is
highly conserved across a range of species from fish to mammals and is highly expressed in …

Abstract Relaxin, insulin-like peptide 3 (INSL3), relaxin-3, and INSL5 are the cognate
ligands for the relaxin family peptide (RXFP) receptors 1–4, respectively. RXFP1 activates …

Fish have provided essential information about the structure, biosynthesis, evolution, and
function of insulin (INS) as well as about the structure, evolution, and mechanism of action of …

Abstract Relaxin‐3 (RLN3) and its native receptor, relaxin family peptide 3 receptor
(RXFP3), constitute a newly identified neuropeptide system enriched in mammalian brain …

Hippocampal theta rhythm is thought to underlie learning and memory, and it is well
established that “pacemaker” neurons in medial septum (MS) modulate theta activity. Recent …

BACKGROUND Insulin-like factor 3 (INSL3) is a neohormone that has evolved to address
specific mammalian traits, in particular, the first phase of testicular descent towards the …